Chemical affinity of 10-methacryloyloxydecyl dihydrogen phosphate to dental zirconia: Effects of molecular structure and solvents
Chemical affinity of 10-methacryloyloxydecyl dihydrogen phosphate to dental zirconia: Effects of molecular structure and solvents
复制标题
10-甲基丙烯酰氧基癸基磷酸二氢盐对牙科氧化锆的化学亲和力：分子结构和溶剂的影响。
DOI：
10.1016/j.dental.2017.09.013
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发表时间：
2017-12-01
期刊：
影响因子：
5
通讯作者：
Tay, Franklin R.
中科院分区：
文献类型：
--
作者：
Chen, Ying;Lu, Zhicen;Tay, Franklin R.
目标.研究溶剂和改变10-甲基丙烯酰氧癸基磷酸二氢酯（10-MDP）的分子结构是否影响其与氧化钇稳定的四氧化锆多晶（Y-TZP）的化学亲和性。本工作采用X射线光电子能谱、傅里叶变换红外光谱和热力学计算研究了Y-TZP和10-MDP在不同溶剂（丙酮/乙醇/水或混合溶剂）中的化学亲和力。剪切粘结强度（SBS）测试用于评估不同溶剂对10-MDP粘结的影响。此外，通过改变10-MDP分子结构产生了几种磷酸酯单体变体。改变包括延长/缩短间隔物链长度，以及在间隔物链的沿着不同位置处安装羟基或羧基作为侧链。计算了10-MDP变体与四氧化锆形成配合物的热力学参数。所得数据表明，溶剂是10-MDP和Y-TZP之间形成Zr-O-P键所必需的。溶剂影响10-MDP的化学亲和力Y-TZP;丙酮促进最好的键合，其次是乙醇。改变10-MDP的分子结构影响其与Y-TZP的化学亲和力。15-MPDP、12-MDDP、6-羟基-10-MDP和6-羧基-10-MDP在与四氢氧化锆配位时均表现出比10-MDP更高的热力学稳定性。相比之下，2-MEP、5-MPP、10-羟基-MDP、10-羧基-MDP、5，6-二羟基-10-MDP和5，6-二羧基-10-MDP的热力学稳定性较低。10-MDP在溶剂中通过解离与氧化锆配位。改变10-MDP的分子结构理论上会影响其与Y-TZP的化学亲和力。(C)2017由Elsevier Ltd代表牙科材料学会发布。
Objectives. To examine whether solvents and changing the molecular structure of 10-Methacryloyloxydecyl dihydrogen phosphate (10-MDP) affect its chemical affinity to Yttria-stabilized tetragonal zirconia polycrystals (Y-TZP).Methods. The present work investigated the chemical affinity between Y-TZP and 10-MDP dissolved in different solvents (acetone/ethanol/water or mixture) using X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, and thermodynamic calculations. Shear bond strength (SBS) tests were used to evaluate the influence of different solvents on 10-MDP bonding. In addition, several phosphate ester monomer variants were created by changing the 10-MDP molecular structure. Changes included extending/shortening the spacer chain-length, and installing hydroxyl or carboxyl groups as side chains at different positions along the spacer chain. The thermodynamic parameters of the complexes formed between the 10-MDP variants and tetragonal zirconia were evaluated.Results. The acquired data indicated that solvent is necessary for the formation of Zr-O-P bonds between 10-MDP and Y-TZP. Solvents affected the chemical affinity of 10-MDP to Y-TZP; acetone facilitated the best bonding, followed by ethanol. Changing the molecular structure of 10-MDP affected its chemical affinity to Y-TZP. The variants 15-MPDP, 12-MDDP, 6-hydroxyl-10-MDP and 6-carboxy-10-MDP all exhibited higher thermodynamic stability than 10-MDP when coordinated with tetragonal zirconia. In contrast, 2-MEP, 5-MPP, 10-hydroxyl-MDP, 10-carboxy-MDP, 5,6-dihydroxyl-10-MDP and 5,6-dicarboxy-10-MDP exhibited lower thermodynamic stability.Significance. 10-MDP coordinates with zirconia through dissociating in solvents. Changing the molecular structure of 10-MDP theoretically affects its chemical affinity to Y-TZP. (C) 2017 Published by Elsevier Ltd on behalf of The Academy of Dental Materials.