Identification of fluorogenic and quenched benzoxadiazole reactive chromophores
Identification of fluorogenic and quenched benzoxadiazole reactive chromophores
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DOI：
10.1016/j.dyepig.2010.05.007
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发表时间：
2011-01-01
影响因子：
4.5
通讯作者：
Cairo, Christopher W.
中科院分区：
文献类型：
--
作者：
Key, Jessie A.;Cairo, Christopher W.
The Sharpless-Meldal reaction was employed to generate triazole-substituted, alkynyl, azido and tri-azolyl-benzoxadiazole as well as nitro-benzoxadiazole fluorophores Linkage of the triazole to the benzoxadiazole ring at C4 gave chromophores which were fluorogenic, while attachment through NI resulted in quenching The 4-azalo-7-nitrobenzoxadiazole underwent a 470-fold decrease in quantum yield upon conversion to the triazole While, 5-ethynyl-benzoxadiazole exhibited a 48-fold enhancement of quantum yield upon formation of tnazole The modulating effects of solvent polarity, conjugation, and attachment point of the fluorochrome to the tnazole were examined (C) 2010 Elsevier Ltd. All rights reserved.
