Jellyfish envenoming syndromes: unknown toxic mechanisms and unproven therapies

Jellyfish envenoming syndromes: unknown toxic mechanisms and unproven therapies
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DOI:
10.5694/j.1326-5377.2003.tb05040.x
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发表时间:
2003-01-06
影响因子:
11.4
通讯作者:
Wilce, JA
Wilce, JA
中科院分区:
医学2区
文献类型:
--
作者:
Bailey, PM;Little, M;Wilce, JA

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自从2002年初昆士兰两名游客死于Irukandji综合症以来,人们对澳大利亚水母引起的毒液综合征一直非常感兴趣。我们回顾了关于这些毒液综合征、毒液作用机制和治疗的现有知识,重点是致命的盒子水母、Chironex fleckeri和被认为导致Irukandji综合征的一系列水母。目前对水母毒液活性的了解非常有限,许多治疗方法都未经证实,而且是基于轶事。
Interest in envenoming syndromes caused by Australian jellyfish has been intense since the deaths in early 2002 of two tourists in Queensland, attributed to the Irukandji syndrome. We review current knowledge of these envenoming syndromes, mechanisms of venom action and therapy, focusing on the deadly box jellyfish, Chironex fleckeri, and the array of jellyfish thought to cause the Irukandji syndrome. Current understanding of jellyfish venom activity is very limited, and many treatments are unproven and based on anecdote.