A prospective survey of patients with valvular heart disease in Europe:: The Euro Heart Survey on Valvular Heart Disease
A prospective survey of patients with valvular heart disease in Europe:: The Euro Heart Survey on Valvular Heart Disease
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DOI：
10.1016/s0195-668x(03)00201-x
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发表时间：
2003-07-01
影响因子：
39.3
通讯作者：
Vahanian, A
中科院分区：
文献类型：
--
作者：
Iung, B;Baron, G;Vahanian, A
目的确定的特点，治疗，和结果的当代心脏瓣膜病（VHD）患者在欧洲，并检查遵守guidelines.Methods和结果的欧洲心脏调查VHD进行了2001年4月至7月在92个中心，来自25个国家，它包括前瞻性5001成人中度至重度本地VHD，感染性心内膜炎，或以前的瓣膜介入。71.9%的患者患有VHD，28.1%的患者既往接受过干预。平均年龄为64 ± 14岁。主动脉瓣膜返流和二尖瓣返流以退行性病变最多见，二尖瓣狭窄以风湿性病变最多见，85.2%的患者术前行冠状动脉造影。在1269例接受介入治疗的患者中，99.0%的主动脉瓣膜置换术，33.9%的二尖瓣扩张术。46.5%的二尖瓣返流患者接受了狭窄和瓣膜修复术; 31.7%的患者接受了2：1的相关手术。在重度、症状性、单一VHD患者中，31.8%未接受干预，最常见的原因是合并症。在无症状患者中，符合指南的比例介于66.0%和78.5%之间。手术死亡率为
Aims To identify the characteristics, treatment, and outcomes of contemporary patients with valvular heart disease (VHD) in Europe, and to examine adherence to guidelines.Methods and results The Euro Heart Survey on VHD was conducted from April to July 2001 in 92 centres from 25 countries; it included prospectively 5001 adults with moderate to severe native VHD, infective endocarditis, or previous valve intervention. VHD was native in 71.9% of patients and 28.1% had had a previous intervention. Mean age was 64+/-14 years. Degenerative aetiologies were the most frequent in aortic VHD and mitral regurgitation while most cases of mitral stenosis were of rheumatic origin.Coronary angiography was used in 85.2% of patients before intervention. Of the 1269 patients who underwent intervention, prosthetic replacement was performed in 99.0% of aortic VHD, percutaneous dilatation in 33.9% of mitral. stenosis, and valve repair in 46.5% of mitral regurgitation; 31.7% of patients had 2:1 associated procedure. Of patients with severe, symptomatic, single VHD, 31.8% did not undergo intervention, most frequently because of comorbidities. In asymptomatic patients, accordance with guidelines ranged between 66.0 and 78.5%. Operative mortality was