Nail changes in patients infected with human immunodeficiency virus -: A prospective controlled study
Nail changes in patients infected with human immunodeficiency virus -: A prospective controlled study
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DOI：
10.1001/archderm.134.10.1216
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发表时间：
1998-10-01
影响因子：
--
通讯作者：
Grosshans, E
中科院分区：
文献类型：
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作者：
Cribier, B;Mena, ML;Grosshans, E
目的：研究人类免疫缺陷病毒（HIV）感染患者的指甲变化的频率，并评估：这些结果的特异性与HIV阴性对照subjects.Design相比：前瞻性对照研究。通过标准化临床检查（曲率、甲板、颜色、甲真菌病）记录指甲变化。在临床诊断为甲真菌病的情况下，进行真菌学培养。设置：初级保健大学医院。患者：共155例HIV-I阳性患者和103例健康HIV阴性对照受试者，年龄和性别比例相当。干预：无。主要结果测量：临床检查结果。结果：67.7%的HIV阳性患者出现指甲症状，对照组为34.0%（P < 0.05）。
Objectives: To study the frequency of nail changes in a population of human immunodeficiency virus (HIV)infected patients and to evaluate the: specificity of these findings by comparison with HIV-negative control subjects.Design: Prospective controlled study. Nail changes were recorded by a standardized clinical examination (curvature, nail plate, color, onychomycosis). in case of clinical diagnosis of onychomycosis, mycological culture was performed.Setting: Primary care university hospital.Patients: A total of 155 HIV-I-positive patients and 103 healthy HIV-negative control subjects of comparable age and sex ratio.Intervention: None.Main Outcome Measure: Clinical examination findings.Results: Nail symptoms were present in 67.7% of HIV-positive patients vs 34.0% of controls (P