The use of salivary steroids to monitor circadian rhythmicity on expeditions in the arctic.
The use of salivary steroids to monitor circadian rhythmicity on expeditions in the arctic.
复制标题
在北极探险中使用唾液类固醇监测昼夜节律。
DOI：
10.3109/07420528509055542
复制
发表时间：
1985
影响因子：
2.8
通讯作者：
K. Griffiths
中科院分区：
文献类型：
--
作者：
I. Campbell;D. Wilson;R. Walker;K. Griffiths
研究人员对四名男子的唾液皮质醇浓度的昼夜变化进行了研究，分别是徒步穿越格陵兰冰盖和夏季前往斯匹茨卑尔根探险时唾液皮质醇和睾丸激素的变化。在这两种情况下，在离开英国之前和整个探险过程中都表现出了昼夜节律。尽管在斯匹茨卑尔根，皮质醇和睾酮在8小时的剧烈相移后出现分离，但节律的初相与两次探险活动模式的变化一致。两国的皮质醇水平都高于英国，但差异在统计学上并不显著。这项工作证明了在排除频繁血液采样的情况下，使用唾液类固醇浓度来研究其昼夜节律性的可行性。
The circadian variation in salivary cortisol concentration was investigated in four men during a traverse on foot, of the Greenland ice cap and of salivary cortisol and testosterone on a summer expedition to Spitzbergen. In both instances circadian rhythmicity was demonstrated both before leaving the U.K. and throughout the expedition. The acrophase of the rhythms followed the changes in activity patterns on both expeditions although there was a dissociation between the cortisol and testosterone following an acute 8 hr phase shift in Spitzbergen. The mesor of cortisol in both instances tended to be higher than in the U.K. but the difference was never statistically significant. This work demonstrates the feasibility of using salivary steroid concentrations to investigate their circadian rhythmicity in circumstances where frequent blood sampling would be precluded.