The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial
The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial
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DOI：
10.1007/s10103-012-1159-3
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发表时间：
2013-01-01
影响因子：
2.1
通讯作者：
Casati, Marcio Z.
中科院分区：
文献类型：
--
作者：
Campos, Gisele N.;Pimentel, Suzana P.;Casati, Marcio Z.
残余袋是具有挑战性的网站，需要额外的牙周治疗。本研究的目的是评价单次光动力疗法（PDT）作为洁治和根面平整（SRP）辅助治疗单根牙残根袋的效果。在全身健康的受试者中进行了一项盲法、分口、随机对照临床试验，这些受试者在支持性牙周治疗中在单根牙中存在至少两个残余牙周袋（探测牙周袋深度（PPD）为每千日元5 mm的一部分，探测时出血（BoP））。选定的研究中心被分配接受（1）PDT + SRP或（2）SRP。在接受PDT治疗的部位，激光系统包括波长为660 nm、功率输出为60 mW、能量密度为129 J/cm（2）的手持式电池供电二极管激光器，以及作为光敏剂的亚甲蓝（10 mg/ml）。在基线和治疗后3个月评估临床参数。两种治疗后临床参数均显著改善（p < 0.05），而PDT + SRP组在3个月时观察到更高的探诊囊袋深度减少和临床附着水平增加（p < 0.05）。此外，与仅通过常规SRP治疗的部位相比，通过组合方法治疗的部位在3个月后PPD < 5 mm且无BoP的部位数量显著减少（p < 0.05）。PDT作为机械清创术的一种辅助手段，对单根牙的残余牙周袋具有额外的临床益处，可能是支持性牙周维护的替代治疗策略。
Residual pockets are challenging sites that require additional periodontal therapy. The aim of this study was to evaluate the effect of a single photodynamic therapy (PDT) as an adjunct to scaling and root planning (SRP) in residual pockets in single-rooted teeth. A blind, split-mouth, randomized controlled clinical trial was conducted in systemically healthy subjects presenting at least two residual pockets (probing pocket depth (PPD) a parts per thousand yen5 mm with bleeding on probing (BoP)) in single root teeth in supportive periodontal therapy. The selected sites were assigned to receive (1) PDT + SRP or (2) SRP. In sites treated by PDT as adjunctive to SRP, the laser system included a handheld battery-operated diode laser with a wavelength of 660 nm, a power output of 60 mW, and energy density of 129 J/cm(2), together with methylene blue as a photosensitizer (10 mg/ml). Clinical parameters were assessed at baseline and 3 months post-therapies. Clinical parameters improved significantly after both therapies (p < 0.05), whereas higher probing pocket depth reduction and clinical attachment level gain were observed in the PDT + SRP group at 3 months (p < 0.05). In addition, sites treated by the combined approach yielded a significant reduction in the number of sites with PPD < 5 mm without BoP after 3 months compared to sites treated by conventional SRP alone (p < 0.05). PDT as an adjunctive to mechanical debridement demonstrated additional clinical benefits for residual pockets in single-rooted teeth and may be an alternative therapeutic strategy in supportive periodontal maintenance.