Hypertension in Relation to Posttraumatic Stress Disorder and Depression in the US National Comorbidity Survey
Hypertension in Relation to Posttraumatic Stress Disorder and Depression in the US National Comorbidity Survey
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DOI：
10.3200/bmed.34.4.125-132
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发表时间：
2009-12-01
影响因子：
2.3
通讯作者：
Ma, Mindy
中科院分区：
文献类型：
--
作者：
Kibler, Jeffrey L.;Joshi, Kavita;Ma, Mindy
临床文献越来越多地表明，心血管危险因素和心血管疾病（CVD）在创伤后应激障碍（PTSD）患者中更为常见。抑郁症也会导致心血管疾病，并经常与创伤后应激障碍共病。迄今为止的研究还没有确定PTSD是否与额外的CVD风险相关，而不仅仅是与共病抑郁症相关的风险。作者在美国全国科摩罗调查的数据中研究了终身创伤后应激障碍和抑郁与高血压的关系。他们将参与者分为4个相互排斥的诊断组：（1）PTSD病史和无抑郁病史，（2）PTSD和抑郁病史，（3）抑郁病史和无PTSD病史，（4）无精神障碍病史PTSD，无抑郁症和PTSD+抑郁症组的高血压患病率高于抑郁症和无精神障碍组。PTSD似乎与高血压相关，与抑郁无关。这可能部分解释了PTSD患者CVD发生率的升高。
The clinical literature increasingly indicates that cardiovascular risk factors and cardiovascular disease (CVD) are more common among individuals with posttraurnatic stress disorder (PTSD). Depression also poses a risk for CVD and is often comorbid with PTSD. Research to date has not established whether PTSD is associated with additional CVD risk beyond the risks associated with comorbid depression. The authors examined relationships of lifetime PTSD and depression with high blood pressure in data from the US National Comorbidity Survey. They divided participants into 4 mutually exclusive diagnostic groups: (1) PTSD history and no depression history, (2) PTSD and depression history, (3) depression history and no PTSD history, and (4) no history of mental disorder Hypertension prevalence was higher for the PTSD, no depression and PTSD plus depression groups compared with the depression only and no mental disorder groups. PTSD appears to be related to hypertension independent of depression. This may partially explain elevated rates of CVD in PTSD patients.