Laser textured Co-Cr-Mo alloy stored chitosan/poly(ethylene glycol) composite applied on artificial joints lubrication
Laser textured Co-Cr-Mo alloy stored chitosan/poly(ethylene glycol) composite applied on artificial joints lubrication
复制标题
激光织构Co-Cr-Mo合金储存壳聚糖/聚乙二醇复合材料在人工关节润滑中的应用
DOI：
10.1016/j.msec.2017.03.195
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发表时间：
2017-09-01
影响因子：
7.9
通讯作者：
Dong, Guangneng
中科院分区：
文献类型：
--
作者：
Lu, Hailin;Ren, Shanshan;Dong, Guangneng
由于体液作为润滑剂的性能较差，关节置换术带来了磨损问题。用于人工关节的润滑剂在注射后会迅速降解并被人体吸收。为了延长润滑油的使用寿命，本研究制备了壳聚糖/聚乙二醇（CS/PEG）和织构，以起到关节润滑和磨损保护的作用。壳聚糖（CS）和聚乙二醇（乙二醇）具有生物相容性和可生物降解性，可用于人体。摩擦学结果表明，当CS和PEG的质量分数分别为2 wt%和30 wt%时，CS/PEG溶胶具有优异的摩擦学性能，在30 ~ 90 N载荷（压力4.2 ~ 12.6 MPa）下，平均摩擦系数小于0.016。本研究将CS/PEG加入人工关节织构中，通过NaOH固化作用使CS/PEG表面形成凝胶。CS/PEG凝胶膜可以防止CS/PEG溶胶在体液中的稀释。同时，FT-IR、XRD、UV/vis和Raman光谱分析表明，CS通过氢键效应与PEG结合，形成特殊的结构，具有良好的摩擦学性能。本研究为提高人工关节的摩擦学性能提供了一种新的、简单的、绿色的方法。(C) 2017年Elsevier B.V.出版
Arthroplasty brings the wear problems because of body fluid has poor performance as lubricant. Lubricant which is used in artificial joints will rapidly degrade and be absorbed by human body after injecting. To prolong the lubricant's effectiveness, this study prepared chitosan/poly(ethylene glycol) (CS/PEG) and textures to play a role in joint lubrication and wear protection. Chitosan (CS) and poly(ethylene glycol) which have biocompatibility and biodegradability properties can be used in human body. The tribological results shown that CS/PEG sol has excellent performance when this sol was composed by 2 wt% CS and 30 wt% PEG, the average friction coefficient below 0.016 under the condition of 30-90 N load (pressure 4.2-12.6 MPa). In this study, CS/PEG was added in the texture of artificial joints, then the surfaces of the CS/PEG formed gel via NaOH solidification effect. The CS/PEG gel film could prevent the CS/PEG sol from diluting in body fluid. Meanwhile, FT-IR, XRD, UV/vis and Raman spectra revealed that CS associated with PEG via hydrogen bond effect may form a particular structure, which leaded the good tribological performance. This study provides a new, simple and green approach to enhance tribological performances of artificial joints. (C) 2017 Published by Elsevier B.V.