Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young adults
Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young adults
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DOI：
10.1016/0006-3223(95)00188-3
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发表时间：
1996-03-15
影响因子：
10.6
通讯作者：
Andreski, P
中科院分区：
文献类型：
--
作者：
Breslau, N;Roth, T;Andreski, P
在一项对年轻人的纵向流行病学研究中，我们对睡眠障碍和精神障碍之间的关联进行了横断面和前瞻性的评估。从密歇根州一家大型健康维护组织(HMO)的所有21-30岁成员中随机抽取了1200人；1989年采访了1007人，1992年重新调查了979人。终生单独失眠的患病率为16.6%，单独过度睡眠的患病率为8.2%，失眠加过度睡眠的终生患病率为8%。在基准期，有失眠史的人在随访期内新发严重抑郁症的性别调整后的相对风险为4.0(95%可信区间[CI]2.2-7.0)，而有高睡眠基准史的人发生严重抑郁的性别调整后的相对危险度为2.9(95%可信区间1.5-5.6)。当控制了其他先前抑郁症状的病史(例如，精神运动迟缓或激越、自杀意念)时，先前的失眠仍然是随后严重抑郁的重要预测因素。几乎每晚主诉两周或更长时间的失眠可能是随后出现严重抑郁症的一个有用的标志。
In a longitudinal epidemiological study of young adults, we estimated the association between sleep disturbance and psychiatric disorders, cross-sectionally and prospectively. A random sample of 1200 was drawn from all 21-30-year-old members of a large health maintenance organization (HMO) in Michigan; 1007 were interviewed in 1989 and 979 were reintewiewed in 1992. Lifetime prevalence of insomnia alone was 16.6%, of hypersomnia alone, 8.2%, and of insomnia plus hypersomnia, 8%. The gender-adjusted relative risk for new onset of major depression during the follow-up period in persons with history of insomnia at baseline was 4.0 (95% confidence interval [CI] 2.2-7.0) and in persons with baseline history of hypersomnia, 2.9 (95% CI 1.5-5.6). When history of other prior depressive symptoms (e.g., psychomotor retardation or agitation, suicidal ideation) was controlled for, prior insomnia remained a significant predictor of subsequent major depression. complaints of 2 weeks or more of insomnia nearly every night might be a useful marker of subsequent onset of major depression.