Carbocisteine inhibits oxidant‐induced apoptosis in cultured human airway epithelial cells
Carbocisteine inhibits oxidant‐induced apoptosis in cultured human airway epithelial cells
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DOI：
10.1111/j.1440-1843.2009.01594.x
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发表时间：
2009-09
期刊：
影响因子：
6.9
通讯作者：
Motoki Yoshida;K. Nakayama;H. Yasuda;H. Kubo;K. Kuwano;H. Arai;M. Yamaya
中科院分区：
文献类型：
--
作者：
Motoki Yoshida;K. Nakayama;H. Yasuda;H. Kubo;K. Kuwano;H. Arai;M. Yamaya
背景和目的：氧化剂水平升高与COPD加重相关，而L-羧甲司坦（一种粘液溶解剂）可降低加重频率。在人气道上皮细胞的体外研究中，检查了L-羧甲司坦对氧化剂诱导的COPD急性加重的抑制作用的潜在机制。
Background and objective: Increased oxidant levels have been associated with exacerbations of COPD, and L‐carbocisteine, a mucolytic agent, reduces the frequency of exacerbations. The mechanisms underlying the inhibitory effects of L‐carbocisteine on oxidant‐induced COPD exacerbations were examined in an in vitro study of human airway epithelial cells.