Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells

Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells
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邻苯二甲酸单-2-乙基己酯诱导 HepG2 细胞线粒体膜电位丧失和 Caspase3 激活

DOI:
10.1016/j.etap.2012.02.001
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发表时间:
2012-05-01
影响因子:
4.3
通讯作者:
Yuan, Jing
Yuan, Jing
中科院分区:
环境科学与生态学3区
文献类型:
--
作者:
Chen, Xi;Wang, Jianshu;Yuan, Jing

文献摘要

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L02 and HepG2 cells were exposed to mono-(2-ethylhexyl) phthalate (MEHP) at concentrations of 6.25-100 mu M. After 48 h treatment, MEHP decreased HepG2 cell viability in a concentration-dependent manner and L02 cell viability in the 50 and 100 mu M groups (p= 25 mu M (p