Gardner's syndrome associated with periampullary carcinoma, duodenal and gastric adenomatosis
Gardner's syndrome associated with periampullary carcinoma, duodenal and gastric adenomatosis
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加德纳综合征与壶腹周围癌、十二指肠和胃腺瘤病相关
DOI：
10.1007/bf02553308
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发表时间：
1982
影响因子：
3.9
通讯作者：
Y. Morioka
中科院分区：
文献类型：
--
作者：
K. Sugihara;T. Muto;J. Kamiya;F. Konishi;T. Sawada;Y. Morioka
一名48岁男性Gardner’s综合征患者，1962年因直肠癌行腹部会阴切除术，发现十二指肠溃疡生长，并于1979年行胰十二指肠切除术。病理检查发现1例分化良好的腺癌伴腺瘤残余，1例大腺瘤伴局灶性癌，256例十二指肠腺瘤，91例胃窦腺瘤。回顾国内外医学文献，对29例壶腹周围癌和12例胃癌合并家族性大肠息肉病或Gardner综合征的病例进行分析。
A 48-year-old man with Gardner's syndrome, who had abdominoperineal resection for rectal carcinoma in 1962, was found to have an ulcerating growth of the duodenum, and pancreaticoduodenectomy was performed in 1979. Histologic examination by complete step-serial sectioning disclosed a well-differentiated adenocarcinoma with adenomatous remnants, a large adenoma with focal carcinoma, 256 adenomas of the duodenum, and 91 adenomas of the gastric antrum. The world medical literature was reviewed, and 29 cases of periampullary carcinoma and 12 cases of gastric carcinoma complicating familial polyposis coli or Gardner's syndrome were analyzed.