The absolute configuration of ecklonialactones A, B, and E, novel oxylipins from brown algae of the genera Ecklonia and Egregia.
The absolute configuration of ecklonialactones A, B, and E, novel oxylipins from brown algae of the genera Ecklonia and Egregia.
复制标题
Ecklonia 和 Egregia 属褐藻中的新型氧脂素 Ecklonialactones A、B 和 E 的绝对构型。
DOI：
10.1021/np50103a028
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发表时间：
1994
影响因子：
5.1
通讯作者：
Gerwick,WH
中科院分区：
文献类型：
--
作者：
Todd,JS;Proteau,PJ;Gerwick,WH
以前从棕色的假单胞菌Ecklonia stolonifera中分离出的Ecklonialactone A、B和E已从俄勒冈州的褐藻Egregia menziesii中分离出。通过各种核磁共振技术独立确定了海葵内酯E的结构和相对立体化学。通过二苯甲酸酯衍生物的cd分析，推测了酮A的绝对立体化学，表明它具有115，121？，一百三十五，一百五十一？，165立体化学相似的1H-和13 C-NMR数据和旋光度表明，B和E在可比较的立体中心处具有与A相同的立体化学。
Ecklonialactones A, B, and E, previously isolated from the brown alga Ecklonia stolonifera, have been isolated from the Oregon phaeophyte Egregia menziesii. The structure and relative stereochemistry of ecklonialactone E were independently determined by various nmr techniques. The absolute stereochemistry of ecklonialactone A was deduced by cd analysis of a dibenzoate derivative, which indicated it possessed a 115, 121?, 135, 151?, 165 stereochemistry. Similar'H-and 13C-nmr data and optical rotations for all of the ecklonialactones indicate that B and E have the same stereochemistry as A at comparable stereocenters.