AXONAL CONDUCTION-VELOCITY AND FORCE OF SINGLE HUMAN MOTOR UNITS
AXONAL CONDUCTION-VELOCITY AND FORCE OF SINGLE HUMAN MOTOR UNITS
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DOI：
10.1002/mus.880110209
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发表时间：
1988-02-01
期刊：
影响因子：
3.4
通讯作者：
THOMAS, CK
中科院分区：
文献类型：
--
作者：
DENGLER, R;STEIN, RB;THOMAS, CK
我们用微型神经摄影术用的钨微电极选择性地记录了正常人和尺神经或正中神经完整切断者的第一背侧骨间肌和拇短展肌的运动单位。在确定了单个单位的募集阈值和抽动张力(尖峰触发的平均)后，使用表面电极在手腕和肘部刺激其神经。通过调整表面电极的位置和刺激强度，并使用计算机对给定单位的阈值上下的反应进行减法，通常可以识别出同一运动单位对两个部位的刺激的反应，并确定其传导速度。正常人运动单位的抽动张力和募集阈值与运动轴传导速度密切相关。来自患者的初步数据表明，这种方法应该适用于一些神经肌肉疾病的患者。
Tungsten microelectrodes of the type used for microneurography have been used to record motor units selectively from the first dorsal interosseous and abductor pollicis brevis muscles of normal subjects, and patients who had had complete sections of the ulnar or median nerve. After determining the recruitment threshold and the twitch tension (spike-triggered averaging) of a single unit, its nerve was stimulated at the wrist and the elbow using surface electrodes. By adjusting the position of the surface electrode and the stimulus intensity and by using computerized subtraction of responses just above and below threshold for a given unit, the same motor unit could often be identified in response to stimulation at both sites and its conduction velocity determined. The twitch tension and recruitment threshold of the motor units were closely correlated with the conduction velocity of the motor axons in normal subjects. Preliminary data from patients suggests that this method should be applicable to patients with a number of neuromuscular disorders.