Intraoperative and on-site cytopathology consultation: Utilization, limitations, and value

Intraoperative and on-site cytopathology consultation: Utilization, limitations, and value
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DOI:
10.1053/sdia.2002.36030
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发表时间:
2002-11-01
影响因子:
2.3
通讯作者:
Baloch, ZW
Baloch, ZW
中科院分区:
医学3区
文献类型:
--
作者:
Gupta, PK;Baloch, ZW

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术中和现场细胞病理学可以成功地进行了一些涂片准备。标本浓缩技术是首选方法。我们实验室使用的Romanowsky染色剂如Diff Quik是经济、方便、可重复和快速的。有时可以与Ultrafast pap或其他快速染色剂结合使用,以提供良好的核细节。此类评估对于上皮肿瘤的分期和许多中枢神经系统病变的初步诊断最有价值。现场和术中诊断有助于对样本进行分类,以进行其他研究。这减少了周转时间,并使手术具有成本效益并对患者有益。与剥脱标本相比,对“正常”相邻结构的认识和对标本细胞形态学的熟悉对于发展具有高度敏感性和特异性的细胞病理学服务至关重要。版权所有2002,爱思唯尔科学(美国)。All rights reserved.
The intraoperative and on-site cytopathology can be successfully performed with a number of smear preparations. Specimen concentration technique is the preferred method. The Romanowsky stain such as Diff Quik used in our laboratory is economical, convenient, reproducible, and quick. This can be at times combined with Ultrafast pap or other rapid stains, which provide good nuclear details. Such evaluations are most valuable in the staging of epithelial tumors and primary diagnosis of a number of central nervous system lesions. On-site and intraoperative diagnoses help triage the specimens for additional studies. This reduces the turn around time and makes the procedure cost-effective and beneficial to the patient. An awareness of the "normal" adjacent structures and familiarity with the cytomorphology of the specimens in comparison to the exfoliative specimens is critical in developing a cytopathology service with high degree of sensitivity and specificity. Copyright 2002, Elsevier Science (USA). All rights reserved.