Solar Ultraviolet Exposure and Absorbed Irradiance of the Cornea and Anterior Chamber/Lens: A Monitoring Model Using Porcine Eyes in a Manikin
Solar Ultraviolet Exposure and Absorbed Irradiance of the Cornea and Anterior Chamber/Lens: A Monitoring Model Using Porcine Eyes in a Manikin
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角膜和前房/晶状体的太阳紫外线照射和吸收辐照度：在人体模型中使用猪眼的监测模型
DOI：
10.1109/access.2019.2961704
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发表时间：
2020-01-01
期刊：
影响因子：
3.9
通讯作者：
Liu, Yang
中科院分区：
文献类型：
--
作者：
Hua, Hui;Hu, Liwen;Liu, Yang
太阳紫外线（UV）辐射是一种不可避免的环境和物理因素，可导致各种眼部疾病。以往的研究主要集中在急性紫外线辐射对眼损伤的机制上。然而，长期和低水平的日常太阳紫外线照射和紫外线眼部组织的吸收会引起慢性损伤，随着时间的推移累积暴露可能导致与年龄相关的眼病。本研究旨在监测眼组织暴露于阳光和吸收的入射辐射量。我们试图模拟代表性眼组织的实际自然暴露于太阳紫外线辐射。因此，在本研究中，使用双探测器光谱仪测量植入人体模型的猪眼在一系列太阳仰角（SEA）下的暴露量。研究发现，角膜的最大太阳紫外线辐照暴露是水平环境暴露的一半，而前房/透镜的最大太阳紫外线辐照暴露是水平环境暴露的五分之一。角膜的吸收率随着波长的增加而降低，而前房/透镜的吸收率随着波长的增加而增加。总之，本研究使用猪眼建立了一个监测模型，并确定了在高环境太阳紫外线背景下所有SEA下眼组织的绝对和相对暴露/吸收紫外线辐照度。此外，该研究表明，对于个人的眼睛太阳紫外线暴露，吸收的太阳紫外线辐照度的总暴露量的比例变化，由于在SEA和阳光路径长度的变化在一天。这些发现为未来的紫外线研究提供了关于实际暴露和吸收辐照度的数据，并可能为白内障的发生提供基于确定性的参考。
Solar ultraviolet (UV) radiation is an unavoidable environmental and physical factor that contributes to a variety of eye diseases. Previous studies have mostly focused on the mechanism of eye damage caused by acute UV radiation. However, long-term and low-level day-to-day solar UV irradiance and absorption of UV ocular tissue induce chronic damage, and cumulative exposure over time may lead to age-related oculopathy. This study aimed to monitor the exposure of ocular tissue to sunlight and the amount of incident radiation absorbed. We attempted to simulate the actual natural exposure of representative ocular tissue to solar UV radiation. Therefore, in this study, a dual-detector spectrometer was used to measure the exposure, at a range of solar elevation angles (SEAs), of porcine eyes implanted into a manikin. The study found that the maximum solar UV irradiance exposure of the cornea was one-half the horizontal ambient exposure, while that of the anterior chamber/lens was one-fifth the horizontal ambient exposure. The absorption ratio decreased with increasing wavelength for the cornea and increased with increasing wavelength for the anterior chamber/lens. In conclusion, the study established a monitoring model using porcine eyes and determined the absolute and relative exposure/absorbed UV irradiance of ocular tissue at all SEAs in a context with high ambient solar UV. Furthermore, the study indicated that for individual ocular solar UV exposure, the ratio of absorbed to total exposure to solar UV irradiance varied due to changes in the SEA and sunlight path length throughout the day. These findings provide data on actual exposure and absorbed irradiance for future UV studies and might provide an exposure-based reference for cataractogenesis.