Economic evaluation of reamed versus unreamed intramedullary nailing in patients with closed and open tibial fractures: results from the study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures (SPRINT).
Economic evaluation of reamed versus unreamed intramedullary nailing in patients with closed and open tibial fractures: results from the study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures (SPRINT).
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闭合性和开放性胫骨骨折患者铰髓内钉与未铰髓内钉的经济评估：前瞻性评估胫骨骨折患者铰髓内钉的研究结果（SPRINT）。
DOI：
10.1016/j.jval.2010.10.034
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Goeree,Ron
中科院分区：
文献类型：
--
作者：
SPRINTInvestigators;Briel,Matthias;Sprague,Sheila;Heels-Ansdell,Diane;Guyatt,Gordon;Bhandari,Mohit;Blackhouse,Gordon;Sanders,David;Schemitsch,Emil;Swiontkowski,Marc;Tornetta3rd,Paul;Walter,StephenD;Goeree,Ron
Introduction Recently, results from the large, randomized study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures (SPRINT) trial suggested a benefit for reamed intramedullary nail insertion in patients with closed tibial shaft fractures largely based on cost-neutral autodynamizations and a potential advantage for unreamed intramedullary nailing in open fractures. We performed an economic evaluation to compare resource use and effectiveness of reamed and unreamed intramedullary nailing using a cost-utility analysis. Methods We calculated quality-adjusted life years (QALYs) for each patient from a self-administered health utility index 3 questionnaire for the first 12 months following the intramedullary nailing. A convenience sample of 235 SPRINT patients provided data on costs associated with health care resource utilization. All costs are reported in Canadian dollars for the 2008 financial year. Results We found incremental effects of− 0.017 (95% confidence interval [CI]− 0.021–0.058) and− 0.002 (95% CI− 0.060–0.062) QALYs for patients treated with reamed compared with unreamed intramedullary nails in closed and open fractures, respectively. The incremental costs for reamed compared with unreamed intramedullary nailing were $51 Canadian dollars (95% CI− $2298–$2400) in closed tibial fractures and $2546 Canadian dollars (95% CI− $1773–$6864) in open tibial fractures. Unreamed nailing dominated reamed nailing for both closed and open tibial fractures; however, the cost and the utility results had high variability. Conclusion Our economic analysis from a governmental perspective suggests small differences in both cost and effectiveness with large uncertainty between reamed and unreamed intramedullary nailing.
