REVERSIBLE FREE RADICAL GENERATION IN MELANIN GRANULES OF EYE BY VISIBLE LIGHT

REVERSIBLE FREE RADICAL GENERATION IN MELANIN GRANULES OF EYE BY VISIBLE LIGHT
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DOI:
10.1016/0003-9861(63)90058-4
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发表时间:
1963-01-01
影响因子:
3.9
通讯作者:
POLIS, BD
POLIS, BD
中科院分区:
生物学3区
文献类型:
--
作者:
COPE, FW;SEVER, RJ;POLIS, BD

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通过电子自旋共振测量,哺乳动物眼睛的黑色素颗粒在近似生理条件下受到可见光照射时会产生自由基。自由基在光下的产生和在黑暗中的衰变发生在几秒钟的时间内。光或暗条件下自由基的平衡浓度取决于周围溶液中水、氢离子和溶解氧的浓度。黑色素颗粒与视杆细胞和视锥细胞的解剖学接近性及其对光的反应表明黑色素颗粒可能在视觉过程中发挥重要作用。
By electron-spin resonance measurements, the melanin granules of the mammalian eye have been shown to generate free radicals when irradiated with visible light under approximately physiological conditions. The generation in the light and decay in the dark of the free radicals takes place over a period of seconds. The equilibrium concentration of free radicals in light or dark is dependent on the concentration of water, hydrogen ions, and dissolved oxygen in the surrounding solution. The anatomical proximity of the melanin granules to the rods and cones and their response to light suggests that the melanin granules may play an important role in the visual process.