Global Epidemiology of Tuberculosis
Global Epidemiology of Tuberculosis
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DOI：
10.1101/cshperspect.a017798
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发表时间：
2015-02-01
影响因子：
5.4
通讯作者：
Raviglione, Mario
中科院分区：
文献类型：
--
作者：
Glaziou, Philippe;Sismanidis, Charalambos;Raviglione, Mario
尽管有有效的化疗，但结核病在2012年造成130万人死亡。与艾滋病毒一样，它仍然是传染病死亡的首要原因。在千年发展目标（MDGs）的背景下，遏制结核病伙伴关系为2015年和2050年制定了减少结核病流行病学负担的全球目标。实现这些目标是国家和国际结核病控制工作的重点，显示这些目标是否实现对指导未来和可持续投资至关重要。本文简要概述了用于估算结核病负担的数据来源;介绍了2012年结核病发病率、患病率和死亡率的估计值，并根据1990年以来的趋势和到2015年的预测，评估了实现2015年减少这些指标的目标的进展情况;分析了结核病报告和控制结核病战略实施的趋势;并考虑了2015年后消除结核病的前景。
Despite the availability of effective chemotherapy, tuberculosis (TB) killed 1.3 million people in 2012. Alongside HIV, it remains a top cause of death from an infectious disease. Global targets for reductions in the epidemiological burden of TB have been set for 2015 and 2050 within the context of the Millennium Development Goals (MDGs) and by the Stop TB Partnership. Achieving these targets is the focus of national and international efforts in TB control, and showing whether or not they are achieved is of major importance to guide future and sustainable investments. This article provides a short overview of sources of data to estimate TB disease burden; presents estimates of TB incidence, prevalence, and mortality in 2012 and an assessment of progress toward the 2015 targets for reductions in these indicators based on trends since 1990 and projections up to 2015; analyzes trends in TB notifications and in the implementation of the Stop TB Strategy; and considers prospects for elimination of TB after 2015.