Kasai procedure improves nutritional status and decreases transplantation-associated complications
Kasai procedure improves nutritional status and decreases transplantation-associated complications
复制标题
Kasai 手术可改善营养状况并减少移植相关并发症
DOI：
10.1007/s00383-018-4228-2
复制
发表时间：
2018-01
影响因子：
1.8
通讯作者：
Jiexiong Feng
中科院分区：
文献类型：
--
作者：
Jixin Yang;Jiexiong Feng
背景本研究的目的是回顾性调查加塞手术（KP）是否改善了胆道闭锁（BA）患儿的营养状况，以及KP是否减少了肝移植（LT）相关并发症。方法从2014年3月1日至2015年2月28日，103例患者接受了LT，另外17例既往未接受KP的患者在等待期间死亡。在103例接受LT的患者中，58例患者既往接受过KP（A组），45例仅接受了直接LT（B组）。结果与B组比较，A组患者行LT的时间间隔明显延长（p < 0.05），B组患者行LT的时间间隔明显缩短（p< 0.05）。A组的体重、白蛋白和血红蛋白均显著高于B组（均P< 0.0001）。与B组相比，A组胆红素、ALT/AST和PELD评分均降低A组术后严重感染和低白蛋白血症发生率明显低于B组结论KP能改善肝移植患者的营养状况，保护肝功能，降低LT术后严重感染和低白蛋白血症的发生率。心理健康可以改善父母的孩子接受过以前的KP。
BackgroundThe aim of this study was to retrospectively investigate whether Kasai Procedure (KP) improves nutritional status and whether KP decreases liver transplantation (LT)-associated complications in children with biliary atresia (BA).MethodsFrom March 1st 2014 to February 28th 2015, 103 patients underwent LT and the other 17 without prior KP died during the waiting period. In 103 patients undergoing LT, 58 patients received KP previously (Group A), and 45 only underwent primary LT (Group B). The nutritional status, liver function and LT-related short-term complications were analyzed.ResultsCompared to Group B, patients in Group A had significantly increased time interval when undergoing LT (p< 0.05). Persistently, the bodyweight, albumin and hemoglobin in Group A were significantly increased compared to Group B (all,p< 0.0001). The bilirubin, ALT/AST and PELD score in Group A were all decreased compared to Group B (p< 0.05) prior to LT. The incidences of post-LT severe infection and hypoalbuminemia in Group A were significantly lower than those of Group B (p< 0.05).ConclusionsKP improves the nutritional status, preserves liver function for patients who finally undergo LT, and decreases the incidence post-LT severe infection and hypoalbuminemia. Mental health can be improved in parents whose children underwent previous KP.
登录
查看更多内容
影响因子：
9
作者：
Superina R;Magee JC;Brandt ML;Healey PJ;Tiao G;Ryckman F;Karrer FM;Iyer K;Fecteau A;West K;Burns RC;Flake A;Lee H;Lowell JA;Dillon P;Colombani P;Ricketts R;Li Y;Moore J;Wang KS;Childhood Liver Disease Research and Education Network
通讯作者：
Childhood Liver Disease Research and Education Network
影响因子：
2.1
作者：
D. Wagner;C. Adunka;D. Kniepeiss;E. Jakoby;S. Schaffellner;M. Kandlbauer;A. Fahrleitner-Pammer;R. Roller;P. Kornprat;H. Müller;F. Iberer;K. Tscheliessnigg
通讯作者：
D. Wagner;C. Adunka;D. Kniepeiss;E. Jakoby;S. Schaffellner;M. Kandlbauer;A. Fahrleitner-Pammer;R. Roller;P. Kornprat;H. Müller;F. Iberer;K. Tscheliessnigg
DOI：
10.1097/01.mpg.0000189339.92891.64
发表时间：
2006-02-01
影响因子：
2.9
作者：
Hung, PY;Chen, CC;Chang, MH
通讯作者：
Chang, MH
胆道闭锁患者Kasai门肠吻合术后术前营养状况及其对胆管炎的影响
影响因子：
1.8
作者：
Li, Dandan;Chen, Xiaoai;Feng, Jiexiong
通讯作者：
Feng, Jiexiong
影响因子：
2.4
作者：
Sandler, AD;Azarow, KS;Superina, RA
通讯作者：
Superina, RA