Measurement of articular cartilage volumes in the normal knee by magnetic resonance imaging: can cartilage volumes be estimated from physical characteristics?
Measurement of articular cartilage volumes in the normal knee by magnetic resonance imaging: can cartilage volumes be estimated from physical characteristics?
复制标题
DOI：
10.1007/s00776-005-0889-5
复制
发表时间：
2005-05-01
影响因子：
1.7
通讯作者：
Matsushita, T
中科院分区：
文献类型：
--
作者：
Nishimura, K;Tanabe, T;Matsushita, T
近年来，一些研究已经进行了磁共振成像（MRI）序列成像软骨。脂肪抑制的三维序列就是这样一个值得注意的例子。最近的研究报道，膝关节软骨的总体积可以用这个序列来阐明。基于这些研究，我们假设膝关节软骨的总体积可能反映了某些其他物理特征。本研究的目的是利用MRI阐明健康成人膝关节髌骨和股骨的关节软骨体积，并分析这些体积与其他身体特征的相关性。该材料包括68名日本健康志愿者的68个膝盖，年龄从20多岁到40多岁（37名男性和31名女性），他们过去没有关节疾病或腿部创伤史。通过MRI对膝关节进行脂肪抑制的三维序列成像，并通过计算机处理计算软骨体积。分析的因素包括年龄、体重、身高、腿长、脚长、大腿和小腿周长、股骨内侧和外侧髁之间的距离、胫骨头直径、体重指数、一般关节松弛度、股四头肌角度和腿跟对线。平均软骨体积为7.6 +/- 1.6cm(3)(男性8.3 +/- 1.6cm（3)，女性6.7 +/- 0.9 cm(3)）。这在男性中明显大于女性。然而，体积与体重、身高、腿长和脚大小呈正相关，没有性别和年龄的区别。基于这些数据，进行多元回归分析：软骨体积= 0.113 x高度- 11.053。我们得出的结论是，无论性别，软骨体积取决于身体大小，并且可以从身体大小的因素来估计。
In recent times several studies have been performed on magnetic resonance imaging (MRI) sequences for imaging cartilage. A fat-suppressed three-dimensional sequence is one such noteworthy example. More recent studies have reported that the total volume of cartilage in a knee joint can be elucidated using this sequence. Based on these studies, we hypothesized that the total volume of cartilage in the knee joint may reflect certain other physical characteristics. The purpose of the current study was to clarify the articular cartilage volumes of the patella and femur in the human knee joints of healthy adults using MRI and to analyze the correlation of these volumes with other physical characteristics. The material comprised 68 knees of 68 Japanese healthy volunteers, aged from their twenties to their forties (37 men and 31 women) who had no past history of joint disease or trauma in the legs. The knees were imaged by MRI with a fat-suppressed three-dimensional sequence, and the cartilage volumes were calculated by computer processing. The factors analyzed were age, body weight, height, leg length, foot size, circumferences of the thigh and lower leg, the distance between medial and lateral femoral condyles, the diameter of the tibial head, body mass index, general joint laxity, quadriceps angle, and leg-heel alignment. The mean cartilage volume was 7.6 +/- 1.6cm(3) (8.3 +/- 1.6 cm(3) in men, 6.7 +/- 0.9 cm(3) in women). It was significantly larger in men than in women. However, the volume positively correlated with body weight, height, leg length, and foot size, without distinction of gender or age. Based on these data, a multiple regression analysis was developed: cartilage volume = 0.113 x height - 11.053. We concluded that the cartilage volume depends on physical size regardless of gender, and it can be estimated from factors of physical size.