Light- and temperature-dependence of the melatonin secretion rhythm in the pineal organ of the lamprey, Lampetra japonica.
Light- and temperature-dependence of the melatonin secretion rhythm in the pineal organ of the lamprey, Lampetra japonica.
复制标题
七鳃鳗松果体褪黑激素分泌节律的光和温度依赖性。
DOI：
--
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
A. Fukuda
中科院分区：
文献类型：
--
作者：
M. Samejima;S. Shavali;S. Tamotsu;K. Uchida;Y. Morita;A. Fukuda
为了确定位于松果体器官中的振荡器的特征，我们使用培养物中的松果体器官检查了温度和光对褪黑激素分泌节律的影响。 20℃时，褪黑激素节律明显：白天分泌量少，夜间分泌量高。当温度从20℃降至10℃时，褪黑激素节律消失。当温度从10℃恢复到20℃时，节奏很快又重新出现。对保存在 7 摄氏度的活体七鳃鳗的血浆褪黑激素水平进行了测量，以建立体内低温下褪黑激素的概况：白天和夜间的分泌没有显着差异。在持续光照条件下，通常在主观夜间观察到的褪黑激素升高在 72 小时后变得模糊。当 LD 周期移动 6 小时（相位提前或相位延迟）时，褪黑激素节律发生变化，以保持与 LD 周期相同的相位关系。此重新同步需要几个 LD 周期。结果表明，在培养中，七鳃鳗松果体的褪黑激素分泌节律对光和温度均敏感，而在体内，褪黑激素节律并不是维持七鳃鳗运动活动节律的关键因素。讨论了松果体器官和褪黑激素在七鳃鳗昼夜节律组织中的作用。
To identify the characteristics of the oscillator located in the pineal organ, we examined the effects of temperature and light on melatonin secretion rhythm using pineal organs in cultures. At 20 degrees C, the melatonin rhythm was obvious: low secretion during the daytime and high during the nighttime. When the temperature was lowered from 20 to 10 degrees C, the melatonin rhythm disappeared. When the temperature was returned from 10 to 20 degrees C, the rhythm quickly reappeared. The plasma melatonin level was measured in living lampreys kept at 7 degrees C to establish the melatonin profile at low temperature in vivo: secretion was not significantly different between daytime and nighttime. Under continuous light conditions, the melatonin elevation normally seen during the subjective night became obscure after 72 h. When the LD cycle was shifted by 6 h (phase-advanced or phase-delayed), the melatonin rhythm shifted to remain in the same phase relation to the LD cycle. This re-synchronization took several LD cycles. The results indicate that, in cultures, the melatonin secretion rhythm in the pineal organ of the lamprey is both light- and temperature-sensitive, and that in vivo, the melatonin rhythm is not the critical factor maintaining the locomotor activity rhythm of the lamprey. The role of the pineal organ and melatonin in the circadian organization of the lamprey is discussed.
在昼夜照明或持续黑暗的条件下，检查灌输鳟鱼（Salmo gairdneri）松果体器官的体外褪黑激素分泌情况。
影响因子：
2.7
作者：
Gern,WA;Greenhouse,SS
通讯作者：
Greenhouse,SS
自由奔跑和夹带叙利亚仓鼠的血液和松果体中褪黑激素的昼夜节律和每日节律。
DOI：
10.1677/joe.0.1360065
发表时间：
1993
期刊：
The Journal of endocrinology
影响因子：
--
作者：
Maywood,ES;Hastings,MH;Max,M;Ampleford,E;Menaker,M;Loudon,AS
通讯作者：
Loudon,AS