Scalable electronic readout design for a 100 ps coincidence time resolution TOF-PET system.
Scalable electronic readout design for a 100 ps coincidence time resolution TOF-PET system.
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DOI：
10.1088/1361-6560/abf1bc
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发表时间：
2021-04-14
影响因子：
3.5
通讯作者：
中科院分区：
文献类型：
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我们已经开发了一个可扩展的探测器读出设计的100 ps符合时间分辨率（CTR）的飞行时间（TOF）正电子发射断层扫描（PET）探测器技术。本文研究的基本闪烁探测器是基于2 × 4阵列的3 × 3 × 10 mm ~ 3 '快LGSO：Ce'闪烁晶体与6 × 4阵列的3 × 3 mm ~ 2硅光电倍增管（SiPM）的侧面耦合。我们采用了一种新颖的混合信号前端电子配置和低定时抖动的现场编程门阵列为基础的时间数字转换器的数据采集。使用22 Na点源，在几个SiPM偏置电压、前沿时间拾取阈值和定时通道下，实验获得了> 10000个符合事件。采用3 × 3 × 10 mm ~ 3的“快LGSO”晶体单元，用Teflon带包裹，侧面耦合到3个SiPM的线性阵列上，获得了102.03 ± 1.9 ps的CTR。此外，对于侧面耦合的2 × 4晶体阵列，测得的平均CTR为113.4 ± 0.7ps。在这项工作中提出的读出架构的设计是可扩展的大面积模块探测器的目标是创建第一个TOF-PET系统与100 ps的FWHM CTR。
We have developed a scalable detector readout design for a 100 ps coincidence time resolution (CTR) time of flight (TOF) positron emission tomography (PET) detector technology. The basic scintillation detectors studied in this paper are based on 2 × 4 arrays of 3 × 3 × 10 mm3 ‘fast-LGSO:Ce’ scintillation crystals side-coupled to 6 × 4 arrays of 3 × 3 mm2 silicon photomultipliers (SiPMs). We employed a novel mixed-signal front-end electronic configuration and a low timing jitter Field Programming Gate Array-based time to digital converter for data acquisition. Using a 22Na point source, >10 000 coincidence events were experimentally acquired for several SiPM bias voltages, leading edge time-pickoff thresholds, and timing channels. CTR of 102.03 ± 1.9 ps full-width-at-half-maximum (FWHM) was achieved using single 3 × 3 × 10 mm3 ‘fast-LGSO’ crystal elements, wrapped in Teflon tape and side coupled to a linear array of 3 SiPMs. In addition, the measured average CTR was 113.4 ± 0.7 ps for the side-coupled 2 × 4 crystal array. The readout architecture presented in this work is designed to be scalable to large area module detectors with a goal to create the first TOF-PET system with 100 ps FWHM CTR.
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通讯作者：
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