Potential costs of flexible sigmoidoscopy-based colorectal cancer screening.
Potential costs of flexible sigmoidoscopy-based colorectal cancer screening.
复制标题
基于柔性乙状结肠镜的结直肠癌筛查的潜在成本。
DOI：
10.1016/s0016-5085(96)70001-x
复制
发表时间：
1996
期刊：
影响因子：
29.4
通讯作者：
Lance,P
中科院分区：
文献类型：
--
作者：
Marshall,JR;Fay,D;Lance,P
背景与目的越来越多的证据表明，通过灵活的乙状结肠镜定期筛查，并适当转介腺瘤患者到结肠镜检查，可以显著降低结直肠癌死亡率。需要对这种筛查的全部成本进行估计。这项研究的目的是估计美国50岁及以上的人通过柔性乙状结肠镜定期筛查的年度成本，并将腺瘤患者转诊至结肠镜检查。方法对1995年至2010年期间每年达到50岁的美国人口队列进行柔性乙状结肠镜检查和结肠镜检查的成本分析。确定了美国癌症协会推荐的和其他间隔的重复筛查和监测检查的年总成本。结果在筛查和监测间隔为3年的情况下，1995年年满50岁的人群的年成本将增加到200亿553millionby2010.Annualcostsfortheentirepopulation50yearsofageandoldercouldincreaseby2010tonearly。结论基于乙状结肠镜的结直肠癌灵活筛查的成本可能会根据所选方案的不同而变化多达三倍。
BACKGROUND & AIMSIncreasing evidence shows that periodic screening by flexible sigmoidoscopy with appropriate referral of patients with adenomas to colonoscopy could substantially decrease colorectal cancer mortality rates. Estimates of the complete cost of such screening are needed. The aim of this study was to estimate the annual costs of periodic screening of Americans 50 years and older by flexible sigmoidoscopy with referral of subjects with adenomas to colonoscopy.METHODSCost analysis of flexible sigmoidoscopy, followed by colonoscopy as warranted, in US population cohorts reaching age 50 each year from 1995 to 2010 was performed. Total yearly costs of repeat screening and surveillance examinations at American Cancer Society-recommended and other intervals were determined.RESULTSWith screening and surveillance intervals of 3 years, annual costs for the cohort of individuals turning 50 in 1995 would increase to 553millionby2010.Annualcostsfortheentirepopulation50yearsofageandoldercouldincreaseby2010tonearly 20 billion.CONCLUSIONSThe cost of flexible sigmoidoscopy-based screening for colorectal cancer could vary as much as threefold depending on the protocol chosen.(Gastroenterology 1996 Dec; 111 (6): 1411-7)