Cell death during natural and induced luteal regression in mares
Cell death during natural and induced luteal regression in mares
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DOI：
10.1530/rep.0.1230067
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发表时间：
2002-01-01
期刊：
影响因子：
3.8
通讯作者：
Watson, ED
中科院分区：
文献类型：
--
作者：
Al-zi'abi, MO;Fraser, HM;Watson, ED
在母马中，关于自然和诱导黄体退化过程中发生的细胞死亡类型的信息很少。分别于黄体早期(第3~4天)、黄体中期(第10天)、早期退化(第14天)、晚期退化(第17天(n=4)、12和36h(每组3只))采集黄体。黄体退行性变早期黄体细胞固缩，细胞外圆形致密小体较黄体中期多。经后期回归分析，差异有统计学意义(P
In mares, little information is available on the type of cell death that occurs during natural and induced luteal regression. Corpora lutea were collected from mares in the early luteal phase, days 3-4 (n=4); mid-luteal phase, day 10 (n=5); early regression, day 14 (n=4); late regression, day 17 (n=4); and 12 and 36 h (n=3 per group) after PGF(2alpha) administration on day 10. Histological and ultrastructural sections were examined and TUNEL was used to detect DNA fragmentation. In early luteal regression, there were more pyknotic luteal cells and extracellular round dense bodies compared with the mid-luteal phase. By late regression, there was a significant decline (P