Development of a simulated tongue substrate for in vitro soft "oral" tribology study
Development of a simulated tongue substrate for in vitro soft "oral" tribology study
复制标题
开发用于体外软“口腔”摩擦学研究的模拟舌头基底
DOI：
10.1016/j.foodhyd.2021.106991
复制
发表时间：
2021
影响因子：
10.7
通讯作者：
Chen Jianshe
中科院分区：
文献类型：
--
作者：
Wang Qi;Zhu Yang;Chen Jianshe
食物颗粒之间以及食物颗粒与口腔表面之间的相对运动的摩擦学原理被认为是控制食物口腔加工和感官感知的重要物理机制。各种模拟口腔润滑的体外技术已在文献中报道，但大多数此类方法不能代表口腔特征，特别是基质。因此，有必要揭示人舌的地形特征以及菌状乳头和丝状乳头的形态特征。在此背景下，本研究应用影像学技术对中国青年人的菌状乳头和丝状乳头的分布进行了研究。分析两种类型乳头的分布和平均大小。舌苔丝状乳头密度与舌苔平均粗糙度呈显著负相关（r =-0.47，p < 0.01）。采用模压技术制备了一种模拟舌体表面形貌和力学强度的舌体基底。通过使用水和糖浆溶液作为模型系统在宽范围的滑动速度和表面载荷下进行润滑测试，验证了基底的可靠性。结果表明，该基片为软摩擦计的摩擦学研究提供了可行的应用。
The tribological principle of the relative movement amongst food particles as well as between food particles and oral surface is considered as an important physical mechanism governing food oral processing and sensory perception. Variousin vitrotechniques which mimic oral lubrication have been reported in literature, but most of such approaches were not representative of oral features, in particular the substrate. Therefore, it is necessary to reveal the topographic characteristics of human tongue and the morphological features of fungiform and filiform papillae. With this background, this work applied imaging technique to investigate distributions of the fungiform and filiform papillae among young Chinese subjects. The distribution and average size of the two types of papillae were analyzed. A significant negative correlation was observed between the density of filiform papillae and average tongue roughness (r = −0.47,p< 0.01). A substrate simulating topographic features as well as mechanical strength of human tongue was fabricated using a moulding technique. The reliability of the substrate was verified by lubrication testing over a wide range of sliding speed and surface load, using water and syrup solutions as model systems. Results show that the current substrate provides a feasible application to soft tribometers forin vitrooral tribology study.