Dysregulation of BMP9/BMPR2/SMAD signalling pathway contributes to pulmonary fibrosis and pulmonary hypertension induced by bleomycin in rats
Dysregulation of BMP9/BMPR2/SMAD signalling pathway contributes to pulmonary fibrosis and pulmonary hypertension induced by bleomycin in rats
复制标题
BMP9/BMPR2/SMAD信号通路失调导致博莱霉素诱导的大鼠肺纤维化和肺动脉高压
DOI:
10.1111/bph.15285
复制
发表时间:
2020-11-09
影响因子:
7.3
通讯作者:
Wang, Jian
中科院分区:
文献类型:
--
作者:
Jiang, Qian;Liu, Chunli;Wang, Jian
Pulmonary hypertension related to pulmonary fibrosis is classed as WHO Group III, one of the most common groups which lacks effective treatment options. In this study, we aimed to uncover the underlying mechanisms, particularly the involvement of the BMP9/BMPR2/SMAD signalling pathway, in this subtype of pulmonary hypertension.