Estimation of triterpenoids from Heliotropium marifolium Koen. ex Retz. in vivo and in vitro. I. Antimicrobial screening
Estimation of triterpenoids from Heliotropium marifolium Koen. ex Retz. in vivo and in vitro. I. Antimicrobial screening
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Heliotropium marifolium Koen 中三萜类化合物的估计。
DOI：
10.1002/ptr.759
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发表时间：
2001
影响因子：
7.2
通讯作者：
M. Dubey
中科院分区：
文献类型：
--
作者：
B. Singh;M. Dubey
海芥菜的己烷提取物产生三萜类化合物的混合物：β-谷甾醇、豆甾醇、β-香树脂醇、无水甘草醇-3 β-醇（表无水甘草醇）、环阿屯酮、乙酸β-香树脂醇、无水甘草醇和表无水甘草醇乙酸酯。针对选定的致病性细菌和真菌，例如大肠杆菌、金黄色葡萄球菌、尼日尔曲霉和产黄青霉，测试了分离的三萜类化合物和参考抗生素（庆大霉素/制霉菌素）。测定了各化合物的抑菌圈和活性指数，发现乙酸环氧菲啶酯（IZ = 17; AI = 1.06）的活性最高。 本研究涉及定量和评估其生长抑制效力。据报道，在体内（0.54%）和体外（0.11%）细胞培养中，环木菠萝烯酮是主要的三萜类化合物。版权所有© 2001约翰威利父子有限公司
The hexane extract of Heliotropium marifolium yielded a mixture of triterpenoids: β‐sitosterol, stigmasterol, β‐amyrin, friedelan‐3β‐ol (epifriedelenol), cycloartenone, β‐amyrin acetate, friedelin and epifriedenyl acetate. Isolated triterpenoid and reference antibiotics (gentamycin/mycostatin) were tested against selected pathogenic bacteria and fungi, e.g. Escherichia coli, Staphylococcus aureus, Aspergillus niger and Penicillium chrysogenum. The inhibition zone (IZ) and the activity index (AI) of isolated compounds were recorded and it was found that epifriedenyl acetate (IZ = 17; AI = 1.06) was the most active. The present study deals with the quantification and assessment of their growth inhibitory potency. It has been reported that cycloartenone was the major triterpenoid in both in vivo (0.54%) and in vitro (0.11%) cell cultures. Copyright © 2001 John Wiley & Sons, Ltd.
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DOI：
--
发表时间：
2007
期刊：
影响因子：
--
作者：
橋本 泰幸;他16名;西村 徳行
通讯作者：
西村 徳行