Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland
Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland
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DOI：
10.1016/j.toxicon.2005.02.009
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发表时间：
2005-12-15
期刊：
影响因子：
2.8
通讯作者：
Furey, A
中科院分区：
文献类型：
--
作者：
James, KJ;Gillman, M;Furey, A
In December 1999, domoic acid (DA) a potent neurotoxin, responsible for the syndrome Amnesic Shellfish Poisoning (ASP) was detected for the first time in shellfish harvested in Ireland. Two liquid chromatography (LC) methods were applied to quantify DA in shellfish after sample clean-up using solid-phase extraction (SPE) with strong anion exchange (SAX) cartridges. Toxin detection was achieved using photodiode array ultraviolet (LC-UV) and multiple tandem mass spectrometry (LC-MSn). DA was identified in four species of bivalve shellfish collected along the west and south coastal regions of the Republic of Ireland. The amount of DA that was present in three species was within EU guideline limits for sale of shellfish (20 mu g DA/g); mussels (Mytilus edulis), < 1.0 mu g DA/g; oysters (Crassostrea edulis),
