The first synthesis of marine sesterterpene (+)-scalarolide
The first synthesis of marine sesterterpene (+)-scalarolide
复制标题
首次合成海洋二倍萜( )-scalarolide
DOI：
10.1016/j.tetlet.2009.06.064
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发表时间：
2009-09-02
影响因子：
1.8
通讯作者：
Deng, Wei-Ping
中科院分区：
文献类型：
--
作者：
Meng, Xiang-Jian;Liu, Yang;Deng, Wei-Ping
通过环氧化物开环重排、立体选择性Diels-Alder加成和一锅-丁烯内酯生成三个关键步骤，合成了第一个C12氧合的海洋scalananic酯萜(+)- scalanolide，并确定了天然scalanolide的绝对构型。2009爱思唯尔有限公司版权所有。
The synthesis of the first example of C12 oxygenated marine scalaranic sesterterpenes (+)-scalarolide was achieved through three key steps including the ring-opening rearrangement of epoxide, stereoselective Diels-Alder addition and one-pot gamma-butenolide formation process, and the absolute configuration of natural scalarolide was confirmed. (C) 2009 Elsevier Ltd. All rights reserved.