THE ELECTRON MICROSCOPICAL AND PHYSICAL CHARACTERISTICS OF SMALL ROUND HUMAN FECAL VIRUSES - AN INTERIM SCHEME FOR CLASSIFICATION

THE ELECTRON MICROSCOPICAL AND PHYSICAL CHARACTERISTICS OF SMALL ROUND HUMAN FECAL VIRUSES - AN INTERIM SCHEME FOR CLASSIFICATION
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DOI:
10.1002/jmv.1890090403
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发表时间:
1982-01-01
影响因子:
12.7
通讯作者:
APPLETON, H
APPLETON, H
中科院分区:
医学3区
文献类型:
--
作者:
CAUL, EO;APPLETON, H

文献摘要

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Many of the small round human fecal virus implicated in outbreaks of nonbacterial gastroenteritis were collected together and examined by EM. Negatively stained preparations without the addition of antibody were used so that the surface morphology of the virus particles remained clearly visible. It was apparent that several viruses, previously thought to be simply antigenic variants within the Norwalk group of viruses, show distinct morphological differences and quite clearly belong to other virus groups. By comparing the features of all the viruses examined in this study, both with each other and with standard cell culture strains of enterovirus, parvovirus and calicivirus, it was possible to propose an interim classification scheme, based primarly on the morphological appearance of the particles and supported by estimations of size and buoyant density.