Expression patterns of miR-146a and miR-146b in mastitis infected dairy cattle
Expression patterns of miR-146a and miR-146b in mastitis infected dairy cattle
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乳腺炎感染奶牛中 miR-146a 和 miR-146b 的表达模式
DOI：
10.1016/j.mcp.2016.08.004
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发表时间：
2016-10-01
影响因子：
3.3
通讯作者：
Liu, Shuan
中科院分区：
文献类型：
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作者：
Wang, Xing Ping;Luoreng, Zhuo Ma;Liu, Shuan
本研究报告了感染亚临床、临床和实验性乳腺炎的牛乳腺组织中bta-miR-146 a和bta-miR-146 b表达水平的显著上调。潜在的靶基因参与多种免疫途径。这些结果表明两种miRNA对牛乳腺组织中的炎症反应具有调节功能。(C)2016爱思唯尔有限公司版权所有
This study reports a significant up-regulation of bta-miR-146a and bta-miR-146b expression levels in bovine mammary tissues infected with subclinical, clinical and experimental mastitis. Potential target genes are involved in multiple immunological pathways. These results suggest a regulatory function of both miRNAs for the bovine inflammatory response in mammary tissue. (C) 2016 Elsevier Ltd. All rights reserved.