Functional MRI of language lateralization during development in children

Functional MRI of language lateralization during development in children
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DOI:
10.1080/14992020701448994
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发表时间:
2007-09-01
影响因子:
2.7
通讯作者:
Byars, Anna W.
Byars, Anna W.
中科院分区:
医学3区
文献类型:
--
作者:
Holland, Scott K.;Vannest, Jennifer;Byars, Anna W.

文献摘要

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从婴儿期到成年期,语言功能在大脑中分布的变化都有记录。语言偏侧化的宏观尺度反映了语言发展的动态过程。在这篇综述中,我们总结了一系列功能性MRI研究的语言技能的儿童年龄在5至18岁,无论是典型的发展中国家的儿童和儿童的脑损伤或神经系统疾病,发生在不同的发展阶段,具有不同程度的严重程度。这些研究使用了一系列与fMRI兼容的语言任务,旨在挖掘儿童早期和后期发展的语言技能和词汇技能。
Changes in the distribution of language function in the brain have been documented from infancy through adulthood. Even macroscopic measures of language lateralization reflect a dynamic process of language development. In this review, we summarize a series of functional MRI studies of language skills in children ages of five to 18 years,both typically-developing children and children with brain injuries or neurological disorders that occur at different developmental stages with different degrees of severity. These studies used a battery of fMRI-compatible language tasks designed to tap sentential and lexical language skills that develop early and later in childhood.