LIFE STRESS AND TREATMENT COURSE OF RECURRENT DEPRESSION .1. RESPONSE DURING INDEX EPISODE
LIFE STRESS AND TREATMENT COURSE OF RECURRENT DEPRESSION .1. RESPONSE DURING INDEX EPISODE
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DOI：
10.1037/0022-006x.60.5.718
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发表时间：
1992-10-01
影响因子：
5.9
通讯作者：
FRANK, E
中科院分区：
文献类型：
--
作者：
MONROE, SM;KUPFER, DJ;FRANK, E
关于抑郁症治疗过程和结果的研究在生活压力的影响方面是混合的。在一项对91名复发性抑郁症患者进行的前瞻性研究中，提出了几个问题。在治疗开始前发生的特定形式的压力预测了16周后和更长的干预期后的不良临床反应。在前6周治疗期间发生的特定形式的压力也预测了16周后和延长干预期后的不良反应。严重的压力发生在治疗早期预测更长的时间来达到缓解治疗反应。压力相关的疾病有一个更好的临床结果的想法的概念进行了讨论，并提出生活压力有不同的影响，个人和没有复发性抑郁症。
Research on treatment course and outcome in depression is mixed with respect to the implications of life stress. Several concerns are addressed in a prospective study of 91 individuals treated for recurrent depression. Specific forms of stress occurring before treatment entry predicted a poor clinical response both after 16 weeks and after a more extended intervention period. Specific forms of stress occurring during the 1st 6 weeks of treatment also predicted poor response after 16 weeks and after the extended intervention period. Severe stress occurring early in treatment predicted a longer time to attain relief for treatment responders. Concepts underlying the idea that stress-related disorders have a better clinical outcome are discussed, and it is proposed that life stress has different implications for individuals with and without recurrent depression.