SARS transmission, risk factors, and prevention in Hong Kong.

SARS transmission, risk factors, and prevention in Hong Kong.
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DOI:
10.3201/eid1004.030628
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发表时间:
2004-04
影响因子:
11.8
通讯作者:
Yang X
Yang X
中科院分区:
医学2区
文献类型:
--
作者:
Lau JT;Tsui H;Lau M;Yang X

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我们分析了从香港报告的1192名可能患有严重急性呼吸系统综合症(SARS)的患者那里获得的信息。其中,26.6%为医院工作人员,16.1%为SARS患者家庭成员,可能有二次感染,14.3%为淘大花园居民,4.9%为住院患者,20.1%为非SARS患者的接触者。其余347例患者(29.1%)没有“已知”感染源。排除那些16岁的患者,330名来自“不明来源”的患者被用于1:2匹配的病例对照研究。本病例对照研究的多因素分析显示,曾去过大陆中国、医院或淘大花园是危险因素(优势比OR 1.95~7.63)。此外,经常在公共场所使用口罩、经常洗手和对居室消毒是显著的保护因素(OR 0.36~0.58)。因此,在香港,社区获得性感染并不是主要的传播方式,公共卫生措施对控制SARS疫情做出了重大贡献。
We analyzed information obtained from 1,192 patients with probable severe acute respiratory syndrome (SARS) reported in Hong Kong. Among them, 26.6% were hospital workers, 16.1% were household members of SARS patients and had probable secondary infections, 14.3% were Amoy Garden residents, 4.9% were inpatients, and 20.1% were contacts of SARS patients who were not family members. The remaining 347 case-patients (29.1%) did not have “known” sources of infection. Excluding those <16 years of age, 330 patients with cases from “undefined” sources were used in a 1:2 matched case-control study. Multivariate analysis of this case-control study showed that having visited mainland China, hospitals, or the Amoy Gardens were risk factors (odds ratio [OR] 1.95 to 7.63). In addition, frequent mask use in public venues, frequent hand washing, and disinfecting the living quarters were significant protective factors (OR 0.36 to 0.58). In Hong Kong, therefore, community-acquired infection did not make up most transmissions, and public health measures have contributed substantially to the control of the SARS epidemic.
DOI: 10.1136/jech.57.11.864
发表时间: 2003-11-01
影响因子: 6.3
作者:
Lau, JTF;Yang, X;Kim, JH
通讯作者: Kim, JH
DOI: 10.1056/nejmoa030685
发表时间: 2003-05-15
影响因子: 158.5
作者:
Lee, N;Hui, D;Sung, JJY
通讯作者: Sung, JJY