Physical and mechanical characterization of a porous cement for metaphyseal bone repair.
Physical and mechanical characterization of a porous cement for metaphyseal bone repair.
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DOI：
10.1590/1413-785220152304145751
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发表时间：
2015-07
影响因子：
0.7
通讯作者：
Volpon JB
中科院分区：
文献类型：
--
作者：
Cimatti B;Engel EE;Nogueira-Barbosa MH;Frighetto PD;Volpon JB
与固体丙烯酸水泥相比，具有与松质骨相似的力学性能的大孔水泥可以改善大型骨缺损的治疗。本研究的目的是比较聚甲基丙烯酸甲酯(PMMA)基多孔水泥与松质骨的物理力学性能。分析了发泡组分为10%(G1)、20%(G2)和30%(G3)的圆柱形多孔PMMA水泥样品的抗压强度、孔径、连通性和分布。将结果与牛松质骨(G4)和固体PMMA(G5)样品进行比较。扫描电子显微镜(SEM)显示，所有实验样品(G1-G3)的孔洞呈随机分布，大小从50微米到3毫米不等。Micro-CT显示G2具有较高的孔隙率和较低的孔连通性。G1、G2和G3之间的屈服强度和杨氏模量没有显著差异。与其他组相比，G4样本略有强度和弹性较差。固体PMMA是非常坚固和无弹性的。PMMA基多孔水泥达到了预期的性能。高孔隙率和大而相互连通的毛孔可能允许骨向内生长。类似松质骨的强度和弹性可能会增强对骨重建的机械刺激。观察性描述性研究。
Macroporous cement with mechanical properties similar to cancellous bone may improve the treatment of large bone defects in relation to solid acrylic cement. The aim of this study was to compare physical and mechanical characteristics of a polymethyl methacrylate (PMMA) based porous cement with cancellous bone. Compressive strength and pore size, interconnectivity, and distribution of cylindrical porous PMMA cement samples containing 10% (G1), 20% (G2) or 30% (G3) effervescent components were analyzed. Results were compared to bovine cancellous bone (G4) and solid PMMA (G5) samples. Scanning electron microscopy (SEM) of all experimental samples (G1 - G3) revealed a random distribution and a wide size variation of pores ranging from 50 µm to 3 mm. Micro-CT showed that G2 have high porosity and lower interconnectivity of pores. No significant differences in yield strength and Young's modulus were observed among G1, G2 and G3. G4 samples were slightly stronger and less elastic than the other groups. Solid PMMA is extremely strong and inelastic. PMMA based porous cement met the expected characteristics. High porosity with large and interconnected pores may allow for bone ingrowth. Strength and elasticity similar to cancellous bone may enhance mechanical stimuli to bone remodeling. Observational Descriptive Study.