Tracking and factors predicting rising in 'tracking quartile' in blood pressure from childhood to adulthood: Odense Schoolchild Study
Tracking and factors predicting rising in 'tracking quartile' in blood pressure from childhood to adulthood: Odense Schoolchild Study
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DOI：
10.1038/sj.jhh.1000836
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发表时间：
1999-06-01
影响因子：
2.7
通讯作者：
Jacobsen, IA
中科院分区：
文献类型：
--
作者：
Lambrechtsen, J;Rasmussen, F;Jacobsen, IA
这项前瞻性研究确定了追踪的程度，并调查了预测1369名受试者中血压（BP）四分位数升高的因素，这些受试者从儿童期到青年期随访了11年。在900名受试者中，在基线和随访时测量血压、身高、体重、体能和对最大运动试验的血压反应。在两次检查中，将血压、体重、身高和体重指数（BMI）分为性别特异性四分位数。通过检查从基线到随访保持在相同四分位数的趋势和测量乘积矩相关系数来评价跟踪。追踪血压、体重、身高和BMI的上四分位数和下四分位数具有显著性。在随访期间，舒张压保持在上四分位数或下四分位数的比值比范围为1.6至2.4，收缩压为2.1至3.1。人体测量值的相关系数范围为0.57-0.75，舒张压为0.12-0.22，收缩压为0.34-0.36。在11年的随访中，体重或相对体重的变化以及对运动试验的BP反应是预测四分位数上升的因素。在BP的大型纵向研究中，基线BP是预测收缩压、舒张压或收缩压和舒张压四分位数升高的重要因素，这证明了存在不可避免的回归平均值问题。
This prospective study determines the degree of tracking and investigates factors predicting a rise in blood pressure (BP) quartile in a cohort of 1369 subjects who were followed for 11 years from childhood into young adulthood. In 900 of these subjects BP, height, weight, physical fitness and BP responses to a maximal exercise testing were measured both at baseline and at follow-up. BP, weight, height and body mass index (BMI) were divided into sex-specific quartiles at both examinations. Tracking was evaluated by examining the tendency of remaining in the same quartile from baseline to follow-up and by measuring product-moment correlation coefficients. Tracking in the upper and lower quartile for BP, weight, height and BMI were significant. Odds ratios for staying in the upper or lower quartile through the follow-up period ranged from 1.6 to 2.4 for diastolic BP and from 2.1 to 3.1 for systolic BP. The range of correlation coefficients for the anthropometric measurements were 0.57-0.75, for diastolic BP 0.12-0.22 and for systolic BP 0.34-0.36 respectively. Changes in weight or relative weight as well as BP response to an exercise test were the factors which predicted a rise in quartile through the 11 years of followup. The existence of the inevitable regression to the mean problem in large longitudinal studies of BP was demonstrated by the finding of baseline BP being a significant factor in the prediction of rising in systolic, diastolic or both systolic and diastolic BP quartiles.