First experience of carbon-ion radiotherapy for early breast cancer
First experience of carbon-ion radiotherapy for early breast cancer
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DOI：
10.1007/s11604-014-0300-6
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发表时间：
2014-05-01
影响因子：
2.1
通讯作者：
Koba, Yusuke
中科院分区：
文献类型：
--
作者：
Akamatsu, Hiroko;Karasawa, Kumiko;Koba, Yusuke
乳腺癌越来越多地在早期阶段被发现，美国和欧洲已经开始应用针对低风险组肿瘤患者的部分乳房放射治疗，作为全乳房放射治疗的替代方案。基于这些经验，一些研究所尝试使用粒子束进行部分乳房照射，用于早期乳腺癌的术后或根治，但技术上的困难阻碍了它的进展。自2011年以来，美国国家放射科学研究所一直在准备对I期乳腺癌进行彻底的碳离子放射治疗(C-ion RT)，我们于2013年4月进行了第一次治疗。在这篇病例报告中，我们解释了我们的第一次C-ion RT治疗乳腺肿瘤的经验，并介绍了放射治疗技术和初步治疗结果，以供其他机构尝试进行同类治疗时参考。
Breast cancer is increasingly being detected at earlier stages, and partial breast irradiation for patients with low-risk-group tumor has come to be applied in the US and Europe as an alternative to whole-breast irradiation. Based on those experiences, some institutes have tried using particle beams for partial breast irradiation for postoperative or radical intent for early breast cancer, but technical difficulties have hindered its progress. The National Institute of Radiological Sciences has been preparing for carbon-ion radiotherapy (C-ion RT) with radical intent for stage I breast cancer since 2011, and we carried out the first treatment in April 2013. In this case report, we explain our first experience of C-ion RT as a treatment procedure for breast tumor and present the radiation techniques and preliminary treatment results as a reference for other institutes trying to perform the same kind of treatment.