Gastric metastases originating from occult breast lobular carcinoma: diagnostic and therapeutic problems
Gastric metastases originating from occult breast lobular carcinoma: diagnostic and therapeutic problems
复制标题
DOI：
10.1186/1477-7819-6-78
复制
发表时间：
2008-07-25
影响因子：
3.2
通讯作者：
Genova, Gaspare
中科院分区：
文献类型：
--
作者：
Ciulla, Antonio;Castronovo, Gioacchino;Genova, Gaspare
背景资料：乳腺癌是女性最常见的胃肠道转移恶性肿瘤，仅次于恶性黑色素瘤。然而，乳腺癌引起的胃肠道转移是相当罕见的。上消化道是更经常涉及和小叶浸润癌有更大的preelection相比，导管type.Case介绍：作者描述的情况下，70岁的妇女与术前诊断胃未分化髓样型癌，这是第一次表现为隐匿性乳腺癌。癌的原发部位被确定与使用一个面板的选择免疫组化markers.Conclusion：我们的目标是在这种情况下的报告，以提高外科医生和临床医生的认识，以排除乳腺起源的可能性，胃癌发生在女性的情况下，即使在患者没有以前或同时发生的乳腺癌的历史。虽然不是特别常见的事件，但在文献中有报道。原发性胃癌和转移性乳腺癌的鉴别诊断对于制定正确的治疗方案，避免患者不必要的手术治疗至关重要。
Background: Breast cancer is the most frequent malignant tumour to metastasize into the gastrointestinal tract in female and is second only to malignant melanoma. Nevertheless gastrointestinal metastases arising from breast cancer are quite rare. The upper gastrointestinal tract is more frequently involved and lobular infiltrating carcinoma has a greater predilection compared to the ductal type.Case presentation: The authors describe the case of a 70 years old woman with a preoperative diagnosis of gastric undifferentiated medullary - type carcinoma, which was the first manifestation of an occult breast carcinoma. The primary site of carcinoma was identified with the use of a panel of selected immunohistochemical markers.Conclusion: Our goal in this case report is to increase the awareness of surgeons and clinicians to rule out the possibility of mammary origin in circumstance of gastric cancer occurring in female, even in patients without a previous or concurrent history of breast carcinoma. Although not a particularly common event, it is, nevertheless, reported in the literature. The differentiation between primary gastric carcinoma and metastatic breast carcinoma is essential for planning the correct therapeutic approach, in order to avoid the patient unnecessary surgery.