Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits
Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits
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DOI：
10.1038/ng.3567
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发表时间：
2016-07-01
期刊：
影响因子：
30.8
通讯作者：
Jackson, David
中科院分区：
文献类型：
--
作者：
Il Je, Byoung;Gruel, Jeremy;Jackson, David
顶端分生组织是一种干细胞，它平衡了子代细胞的增殖与器官原基的结合。这种平衡是由分生组织顶端的干细胞和底层组织中心之间的CLAVATA-WUSCHEL反馈信号维持的。从器官原基提供反馈以控制植物干细胞生态位的信号也被假设，但它们的身份尚不清楚。在这里，我们报告了FASCIATED EAR3(FEA3)，它是一种亮氨酸重复受体，在干细胞控制中发挥作用，并对器官原基中表达的CLAVATA3/ESR相关(CLE)肽产生反应。我们对我们的结果进行了建模，以提出一个调控系统，该系统将器官原基中分化细胞的信号传输回干细胞生态位，似乎在植物界发挥着广泛的功能。此外，我们还展示了这种新的信号反馈的应用，显示了FIRE3的弱等位基因提高了杂交玉米的产量性状。
Shoot apical meristems are stem cell niches that balance proliferation with the incorporation of daughter cells into organ primordia. This balance is maintained by CLAVATA-WUSCHEL feedback signaling between the stem cells at the tip of the meristem and the underlying organizing center. Signals that provide feedback from organ primordia to control the stem cell niche in plants have also been hypothesized, but their identities are unknown. Here we report FASCIATED EAR3 (FEA3), a leucinerich- repeat receptor that functions in stem cell control and responds to a CLAVATA3/ESR-related (CLE) peptide expressed in organ primordia. We modeled our results to propose a regulatory system that transmits signals from differentiating cells in organ primordia back to the stem cell niche and that appears to function broadly in the plant kingdom. Furthermore, we demonstrate an application of this new signaling feedback, by showing that weak alleles of fea3 enhance hybrid maize yield traits.