Control of Channel Clustering by Cleavage.
Control of Channel Clustering by Cleavage.
复制标题
通过分裂控制通道聚类。
DOI:
10.1016/j.neuron.2020.05.017
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发表时间:
2020
期刊:
影响因子:
16.2
通讯作者:
Salzer,JamesL
中科院分区:
文献类型:
--
作者:
Salzer,JamesL
Enrichment of sodium channels at nodes of Ranvier, a hallmark of myelinated axons, underlies effective saltatory conduction. In this issue ofNeuron, Eshed-Eisenbach et al. (2020) demonstrate that proteolysis of gliomedin, which drives initial channel clustering, provides a novel mechanism to ensure fidelity of channel localization to nodes.