Treadmill training with body weight support: Its effect on Parkinson's disease

Treadmill training with body weight support: Its effect on Parkinson's disease
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DOI:
10.1053/apmr.2000.4439
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发表时间:
2000-07-01
影响因子:
4.3
通讯作者:
Kang, J
Kang, J
中科院分区:
医学1区
文献类型:
--
作者:
Miyai, I;Fujimoto, Y;Kang, J

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目的:目的:探讨减重平板训练(BWSTT)是否能有效改善帕金森病患者的功能预后。患者随机接受为期4周的BWSTT治疗,支持多达20%的体重,然后接受为期4周的常规物理治疗(PT),或以相反的顺序接受相同的治疗。在整个研究过程中,帕金森综合征的药物治疗没有改变。地点:神经系统疾病住院康复单位。受试者:10名患者(男5例,女5例)Hoehn-Yahr 2.5或3期帕金森综合征,平均年龄67.6岁,帕金森病平均病程4.2年。结果:BWSTT治疗前后的总运动耐力评分(TRS)平均为31.6/25.6,PT治疗前后的TRS平均为29.1/28.0。协方差分析显示,治疗类型(F(1,16)= 42.779,p <0.0001)而不是治疗顺序(F(1,16)= 0.157,p = 0.6971)对改善BPRS有显著影响。患者在步行速度方面,BWSTT的改善也明显大于PT(BWSTT,之前/之后= 10.0/8.3; PT,9.5/8.9),以及步数(BWSTT,22.3/19.6; PT,21.5/20.8)。在帕金森病患者中,跑步机训练与体重支持在日常生活活动中产生更大的改善,运动表现和比物理治疗更好的治疗效果。
Objective: To test whether body weight-supported treadmill training (BWSTT) is effective in improving functional outcome of patients with Parkinson's disease.Design: Prospective crossover trial. Patients were randomized to receive either a 4-week program of BWSTT with up to 20% of their body weight supported followed by 4 weeks of conventional physical therapy (PT), or the same treatments in the opposite order. Medications for parkinsonism were not modified throughout the study.Setting: Inpatient rehabilitation unit for neurologic diseases.Subjects: Ten patients (5 men, 5 women) with Hoehn and Yahr stage 2.5 or 3 parkinsonism; mean age 67.6 years, mean duration of Parkinson's disease 4.2 years.Main Outcome Measures: The Unified Parkinson's Disease Rating Scale (UPDRS); ambulation endurance and speed (sec/10m), and number of steps for 10-meter walk.Results: The mean total UPDRS before/after BWSTT was 31.6/25.6, and before/after PT was 29.1/28.0. Analysis of covariance for improvement of UPDRS demonstrated a significant effect of type of therapy (F(1, 16) = 42.779, p < .0001) but not order of therapy (F(1, 16) = 0.157, p = .6971). Patients also had significantly greater improvement with BWSTT than with PT in ambulation speed (BWSTT, before/after = 10.0/8.3; PT, 9.5/8.9), and number of steps (BWSTT, 22.3/19.6; PT, 21.5/20.8).Conclusions: In persons with Parkinson's disease, treadmill training with body weight support produces greater improvement in activities of daily living, motor performance, and ambulation than does physical therapy.