Attention-deficit/hyperactivity disorder risk for heavy drinking and alcohol use disorder is age specific
Attention-deficit/hyperactivity disorder risk for heavy drinking and alcohol use disorder is age specific
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DOI：
10.1111/j.1530-0277.2007.00349.x
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发表时间：
2007-04-01
影响因子：
3.2
通讯作者：
Marshal, Michael P.
中科院分区：
文献类型：
--
作者：
Molina, Brooke S. G.;Pelham, William E.;Marshal, Michael P.
背景：本研究旨在评估儿童时期诊断出患有注意力缺陷/多动症 (ADHD) 的青少年和年轻人中重度饮酒和酒精使用障碍 (AUD) 风险的年龄特异性。方法：在匹兹堡 ADHD 纵向研究中，平均 8 年后对诊断为 ADHD 的儿童（n = 364 名先证者）进行访谈，无论是青少年（11-17 岁）还是年轻人（18-28岁）。招募了人口统计学相似、年龄匹配且无 ADHD 的参与者作为青少年 (n=120) 或成人 (n=120) 与先证者进行比较。对酒精参与情况进行了全面评估，包括酗酒研究中标准的重度饮酒测量以及后来酒精相关问题的预后。结果：结果揭示了该关联的年龄特异性，例如间歇性重度饮酒（每次饮酒 5 杯以上）、醉酒、DSM-IV AUD 症状和 DSM-IV AUD 在 15 至 17 岁先证者中升高，但在年轻青少年中没有升高。在年轻人中，患有反社会人格障碍的先证者的饮酒量和 AUD 较高。还检查了反映反社会行为的童年预测因素。结论：这些发现的年龄特异性有助于解释先前关于多动症儿童酒精相关结果风险的研究中的不一致之处。
Background: This study was designed to assess age specificity in the risk for heavy drinking and alcohol use disorder (AUD) among adolescents and young adults with Attention-Deficit/Hyperactivity Disorder (ADHD) diagnosed in childhood.Methods: Children diagnosed with ADHD (n=364 probands) were interviewed an average of 8 years later in the Pittsburgh ADHD Longitudinal Study, either as adolescents (11-17 years old) or as young adults (18-28 years of age). Demographically similar age-matched participants without ADHD were recruited as adolescents (n=120) or as adults (n=120) for comparison with the probands. Alcohol involvement was assessed comprehensively to include measures of heavy drinking that are standard in alcoholism research and prognostic of later alcohol-related problems.Results: Results revealed age specificity in the association such that episodic heavy drinking (measured as 5+ drinks per occasion), drunkenness, DSM-IV AUD symptoms, and DSM-IV AUD were elevated among 15- to 17-year-old probands, but not among younger adolescents. Among young adults, drinking quantity and AUD were elevated among probands with antisocial personality disorder. Childhood predictors indexing antisocial behavior were also examined.Conclusions: The age- specificity of these findings helps to explain prior inconsistencies across previous studies regarding risk for alcohol-related outcomes among children with ADHD.