Indoor environmental differences between inner city and suburban homes of children with asthma
Indoor environmental differences between inner city and suburban homes of children with asthma
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DOI：
10.1007/s11524-007-9205-3
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发表时间：
2007-07-01
影响因子：
6.6
通讯作者：
Eggleston, Peyton A.
中科院分区：
文献类型：
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作者：
Simons, Elinor;Curtin-Brosnan, Jean;Eggleston, Peyton A.
我们进行了这项研究，以比较环境暴露在郊区家庭的哮喘儿童暴露在内城家庭的哮喘儿童，更好地了解室内污染物暴露的重要差异，可能有助于增加哮喘发病率在内城。室内PM10，PM2.5，NO2，O-3，空气和灰尘过敏原水平进行了测量，在120名哮喘儿童的家中，100个住在市中心巴尔的摩和20个住在周边县。家庭条件和健康结果的措施也进行了比较。市中心和郊区的家庭在可能影响空气环境暴露的方式上有所不同。市中心的家庭有更多的吸烟（67%比5%，p <0.001），失修的迹象（77%比5%，p <0.001），蟑螂（64%比0%，p <0.001）和老鼠（80%比5%，p <0.001）感染。与郊区家庭相比，内城家庭的PM10（47 vs. 18 μ g/m3）、PM2.5（34 vs. 8.7 μ g/m3）、NO2 [19 ppb vs.低于检测（BD）]和O-3（1.9 vs. 015 ppb）的几何平均值（GM）水平更高（p <0.001）。市中心的家庭有较低的转基因卧室灰尘过敏原水平的尘螨（0.29 vs. 1.2 μ g/g，p = 0.022），犬（0.38对5.5 μ g/g，p <0.001）和猫（0.75对2.4 μ g/g，p = 0.039），但小鼠（3.2对0.013 μ g/g，p <0.001）和蟑螂（4.5对0.42 U/g，p <0.001）的水平较高。市中心的家庭也有更高的转基因空气中的小鼠过敏原水平（0.055对0.016 ng/m3，p = 0.002）。与郊区哮喘儿童的家庭相比，巴尔的摩市中心哮喘儿童的家庭空气污染物水平较高，家庭特征使哮喘发病率更高。
We conducted this study to compare environmental exposures in suburban homes of children with asthma to exposures in inner city homes of children with asthma, to better understand important differences of indoor pollutant exposure that might contribute to increased asthma morbidity in the inner city. Indoor PM10, PM2.5, NO2, O-3, and airborne and dust allergen levels were measured in the homes of 120 children with asthma, 100 living in inner city Baltimore and 20 living in the surrounding counties. Home conditions and health outcome measures were also compared. The inner city and suburban homes differed in ways that might affect airborne environmental exposures. The inner city homes had more cigarette smoking (67% vs. 5%, p < .001), signs of disrepair (77% vs. 5%, p < .001), and cockroach (64% vs. 0%, p < .001) and mouse (80% vs. 5%, p < .001) infestation. The inner city homes had higher geometric mean (GM) levels (p < .001) of PM10 (47 vs. 18 mu g/m(3)), PM2.5 (34 vs. 8.7 mu g/m(3)), NO2 [19 ppb vs. below detection (BD)], and O-3 (1.9 vs. .015 ppb) than suburban homes. The inner city homes had lower GM bedroom dust allergen levels of dust mite (.29 vs. 1.2 mu g/g, p = .022), dog (.38 vs. 5.5 mu g/g, p < .001) and cat (.75 vs. 2.4 mu g/g, p = .039), but higher levels of mouse (3.2 vs. .013 mu g/g, p < .001) and cockroach (4.5 vs. .42 U/g, p < .001). The inner city homes also had higher GM airborne mouse allergen levels (.055 vs. .016 ng/m(3), p = .002). Compared with the homes of suburban children with asthma, the homes of inner city Baltimore children with asthma had higher levels of airborne pollutants and home characteristics that predispose to greater asthma morbidity.