A pasteurella-like organism from the human respiratory tract.
A pasteurella-like organism from the human respiratory tract.
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来自人类呼吸道的巴氏杆菌样微生物。
DOI：
10.1002/path.1700830117
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发表时间：
1962
期刊：
影响因子：
--
通讯作者：
D. M. Jones
中科院分区：
文献类型：
--
作者：
D. M. Jones
材料和方法15个巴氏杆菌样菌株是从曼彻斯特公共卫生实验室检查的常规痰标本中分离出来的;在8个月内收到的标本中，约有1%发现了它们。在同一时期，只有两次分离到真正的P. aeptica。所有这些菌株均来自急性或慢性呼吸道感染患者，在每种情况下，在原代血琼脂平板上均存在大量的微生物菌落。通常，也会出现同样严重的嗜热菌或双球菌的生长，肺炎也会出现。目前还不能确定类巴氏杆菌是否是活跃的致病菌，但似乎它们在疾病过程中起着辅助作用。在某些慢性支气管炎和支气管扩张的病例中，同一种微生物在首次分离后几个月又被重新分离出来，这表明在呼吸道中可能存在长期携带。该实验室收到了另一株菌株进行鉴定，G博士好心提供了两株菌株。H.在用于比较的其他菌株中，四种血清学类型的厌氧变形杆菌（AD）各有一种代表，由G。H. Tee、3株溶肠巴氏杆菌（9380、9712、10218）和1株马放线杆菌（B. equirulis no.8529）从国家典型培养物保藏中心获得，两种血清学上代表性的木氏放线杆菌菌株（A6，A13）由D. H.伯明翰大学细菌学系的Till博士。
MATERIALS AND METHODSOrgunkma. Fifteen of the pasteurella-like strains were isolated from routine sputum specimens examined at the Manchester Public Health Laboratory; they were found in about 1 per cent. of the specimens received during 8 months. In the same period true P. aeptica was isolated on only two occasions. All these strains came from patients with acute or chronic respiratory infection, and in each case the colonies of the organism were present in large numbers on the primary blood agar plate. Commonly, an equally heavy growth of Hmmophilw injuenzce or Diplococcw, pneumonia wm also present. It could not be determined whether the pasteurella-like organisms were actively pathogenic, but it seemed that they might have had an auxiliary role in the disease process. In some of the cases of chronic bronchitis and bronchiectasis the same organism was re-isolated several months after its first isolation, showing that there may be prolonged carriage in the respiratory tract. A further strain was received at this laboratory for identification, and two strains were kindly provided by Dr G. H. Tee of the Dor-Chester Public Health Laboratory.Of other strains examined for comparison, one representative of each of the four serological types of P. aeptica (AD) were supplied by Dr G. H. Tee, three strains of Pasteurella hcernolytica (no. 9380, 9712, 10218) and one of Actinobacillus equuli (B. equirulis no. 8529) were obtained from the National Collection of Type Cultures, and two serologically representative strains of Actinobacillus lignieresi (A6, A13) were supplied by Mr D. H. Till of the Department of Bacteriology, University of Birmingham.