History is repeating itself, a probable zoonotic spillover as a cause of an epidemic: the case of 2019 novel Coronavirus.
History is repeating itself, a probable zoonotic spillover as a cause of an epidemic: the case of 2019 novel Coronavirus.
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历史正在重演，可能是人畜共患病的溢出效应导致流行病：2019 年新型冠状病毒的病例。
DOI：
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
S. Esposito
中科院分区：
文献类型：
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作者：
A. Rodríguez;D. Bonilla;G. J. Balbin;A. Rabaan;R. Sah;A. Paniz‐Mondolfi;P. Pagliano;S. Esposito
病原体从脊椎动物传播到人类，也称为人畜共患病溢出，是一种全球公共卫生负担，虽然与多次爆发有关，但仍然是一种知之甚少的现象。冠状病毒，像流感病毒一样，在自然界中的各种动物物种中传播。α-冠状病毒和β-冠状病毒可以感染哺乳动物，γ-冠状病毒和δ-冠状病毒倾向于感染鸟类，但其中一些也可以传播给哺乳动物。虽然仍是初步的，但目前的数据表明，蝙蝠是目前2019年新型冠状病毒（2019 nCoV）爆发的最可能的最初来源，该爆发于2019年12月在中国武汉开始，显然是从“湿市场”传播到中国的多个城市和省份。这种2019年nCoV的流行，今天（2020年1月底）已经达到6,000多例（在中国超过90%），不会是最后一次与人畜共患病溢出事件有关。
Pathogen transmission from a vertebrate animal to a human, also known as zoonotic spillover, represents a global public health burden, which while associated with multiple outbreaks, still remains a poorly understood phenomenon. Coronaviruses, like influenza viruses, circulate in nature in various animal species. Alpha-coronaviruses and beta-coronaviruses can infect mammals and gamma-coronaviruses and delta-coronaviruses tend to infect birds, but some of them can also be transmitted to mammals. Although still preliminary, current data suggest that bats are the most probable initial source of the current 2019 novel CoV (2019nCoV) outbreak, that begun on December 2019 in Wuhan, China, apparently spreading from a "wet market" to multiple cities and provinces in China. This epidemic of 2019nCoV, already reaching more than 6,000 cases to-day (end of January 2020) (>90% in China), will not be the last one linked to zoonotic spillover events.