The Role of Exercise in Amyotrophic Lateral Sclerosis
The Role of Exercise in Amyotrophic Lateral Sclerosis
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DOI：
10.1016/j.pmr.2008.02.003
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发表时间：
2008-08-01
影响因子：
1.7
通讯作者：
Mitsumoto, Hiroshi
中科院分区：
文献类型：
--
作者：
Chen, Amy;Montes, Jacqueline;Mitsumoto, Hiroshi
肌萎缩侧索硬化症（ALS）是一种影响运动神经系统的神经退行性疾病。它会导致患者进行性和累积性的身体残疾，并最终因呼吸肌衰竭而死亡。这种疾病在其表现、病程和进展方面是多样的。我们尚未完全了解这种疾病的原因，也不了解其进展的机制;因此，我们缺乏治疗这种疾病的有效手段。目前，我们依靠多学科的方法来对ALS患者进行药物管理和护理。在这篇文章中，作者回顾了运动在ALS患者中的作用的文献，并简要比较了运动在其他神经肌肉疾病中的作用。
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the motor nervous system. It causes progressive and cumulative physical disabilities in patients, and leads to eventual death due to respiratory muscle failure. The disease is diverse in its presentation, course, and progression. We do not yet fully understand the cause or causes of the disease, nor the mechanisms for its progression; thus, we lack effective means for treating this disease. Currently, we rely on a multidisciplinary approach to symptomatically manage and care for patients who have ALS. In this article, the authors review the literature on the role of exercise in patients who have ALS, and briefly compare what is known about exercise in other neuromuscular diseases.