Optimization of extrusion based ceramic 3D printing process for complex bony designs
Optimization of extrusion based ceramic 3D printing process for complex bony designs
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DOI：
10.1016/j.matdes.2018.11.054
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发表时间：
2019-01-15
影响因子：
8.4
通讯作者：
Kalaskar, Deepak M.
中科院分区：
文献类型：
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作者：
Roopavath, Uday Kiran;Malferrari, Sara;Kalaskar, Deepak M.
在这项研究中，使用基于挤出的3D打印工艺对临床批准的羟基磷灰石（HA）进行了材料和设计优化。使用各种技术确定了各种印刷参数（包括印刷速度、挤出压力、精度和填充密度）对生产规定多孔结构的影响。特别是扫描电子显微镜，微型计算机断层扫描技术已被用来研究内部和外部的准确性。通过力学测试研究了孔隙率对3D打印结构压缩性能的影响，结果表明，3D打印HA支架材料的填充密度与烧结后的收缩率呈线性关系。3D打印支架的孔隙率和机械强度取决于设计的CAD文件的填充密度。定制填充密度还有助于以可预测的方式改变机械性能。最后，一项关于羟基磷灰石打印患者特定骨移植物的案例研究证明了这种材料和技术打印在基于CT的解剖骨模型和术前3D规划上创建的复杂多孔结构的能力，为复杂骨设计的定制植入物开发提供了进一步的希望。(C)2018作者由爱思唯尔有限公司发布
In this study presents materials and design optimization of clinically approved hydroxyapatite (HA) using extrusion based 3D printing process. The effect of various printing parameters including print speed, extrusion pressure, accuracy and infill density to produce defined porous structures is established using various techniques. Particularly Scanning Electron Microscopy, Micro Computed Tomography have been employed to study internal and external accuracy. Mechanical testing was employed to study the effect of porosity on compressive properties of 3D printed structures.This study shows that, the infill density and shrinkage of 3D printed HA scaffolds post sintering have a linear relationship. Porosity and mechanical strength of 3D printed scaffolds depend on the infill density of the designed CAD file. Tailoring infill density also helps in altering mechanical properties in a predictable manner. finally, a case study on hydroxyapatite printing of a patient specific bone graft demonstrates the ability of this material and technique to print complex porous structures created on CT-based anatomical bone models and preoperative 3D planning, providing further promise for custom implant development for complex bony designs. (C) 2018 The Authors. Published by Elsevier Ltd.