Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration
Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration
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DOI：
10.1117/1.jbo.22.3.035005
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发表时间：
2017-03-01
影响因子：
3.5
通讯作者：
Stookey, George K.
中科院分区：
文献类型：
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作者：
Ando, Masatoshi;Ferreira-Zandona, Andrea G.;Stookey, George K.
本研究旨在评估定量光诱导荧光（QLF）使用目视检查（VE）作为金标准评估龋齿病变活动的能力。对 23 名 9 岁至 14 岁儿童的颊面有 24 个可见的白斑病变进行了检查。在基线时，表面用水合，此后，在图像采集过程中用连续压缩空气脱水。 QLF 图像在 0（基线）、5 和 15 秒时采集。记录 QLF 变量 [QLF(V)：荧光损失 (Delta F)、病变大小 (S)、Delta Q：Delta F x S]。确定每秒 QLF(V) 的变化 (Delta QLF(V))：Delta QLF(V) = (QLF(VN) - QLF(VBaseline)/N ，其中 N 表示脱水时间。一位经验丰富的牙医使用牙科综合治疗台的灯光、压缩空气和探测器独立进行 VE。活动组 (n = 11) 的 QLF(V) 和 Delta QLF(V) 使用双样本 t 检验将其与不活动组 (n = 13) 进行比较。随着表面脱水，活性组的 S 和 Delta Q 值增加，而非活性组的 QLFV 仅显示很小的变化。活动组的Delta QLF(V)大于非活动组；然而，差异并未达到统计学显着性（p > 0.11）。在本研究的限制范围内，QLF 数据表明指定为活动性病变的增量和定义为非活动性病变的最小变化。 (C) 2017 年光电仪器工程师协会 (SPIE)
This study aimed to evaluate the ability of quantitative light-induced fluorescence (QLF) to assess caries lesion activity using visual examination (VE) as the gold standard. Twenty-four visible white spot lesions on buccal surfaces were examined from 23 children, ages 9 to 14 years. At baseline, the surface was hydrated with water, and thereafter, it was dehydrated with continuous compressed air during image acquisition. QLF images were acquired at 0 (baseline), 5, and 15 s. QLF variables [QLF(V): fluorescence loss (Delta F), lesion size (S), Delta Q: Delta F x S] was recorded. Changes-in-QLF(V) per second (Delta QLF(V)) were determined:Delta QLF(V) = (QLF(VN) - QLF(VBaseline)/N , where N indicates dehydration time. One experienced dentist conducted VE independently using a dental unit's light, compressed air, and explorer. QLF(V) and Delta QLF(V) of the active group (n = 11) were compared with those of the inactive group (n = 13) using two-sample t-tests. As the surface was dehydrated, S and Delta Q values of the active group increased, whereas QLFV of the inactive group showed only a small change. Delta QLF(V) of the active group were larger than those of the inactive group; however, the difference did not reach statistical significance (p > 0.11). Within the limitations of this study, QLF data indicated increments for lesions designated as active and minimal change for lesions defined as inactive. (C) 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)